Comment un mécanisme de résistance aux antibiotiques favorise la virulence bactérienne. Audrey Goman, Lola Manenc, ..., Priscilla Branchu, et al., médecine/sciences 2026. DOI: 10.1051/medsci/2025252

The role of dietary patterns on epigenetic and inflammatory aging based on the INSPIRE-T study. Natasha Grande de França, Yves Rolland, ..., Nathalie Vergnolle, Jean‐Paul Motta, ..., Céline Deraison, Chrystelle Bonnart, et al., Communications Medicine 2026. DOI: 10.1038/s43856-026-01643-1

Mtb-Timer: a fluorescent reporter to visualize Mycobacterium tuberculosis replication and antibiotic responses. Víctor Campo-Pérez, Chak Hon Luk, et al., mSystems 2026. DOI: 10.1128/msystems.01796-25

High thrombin activity associated with crohn’s disease induces microbiota pathogenicity contributing to mucosal inflammation. Guillaume Le Cosquer, Melissa Pannier, ..., Laura Guiraud, ..., Céline Deraison, Nathalie Vergnolle, Jean‐Paul Motta, Gut Microbes 2026. DOI: 10.1080/19490976.2026.2687903

Intestinal toxicity of functionalized polystyrene nanoplastics in NOD2 models of Crohn’s disease susceptibility. Manon Dussol, Sandrine Ménard, ..., Frédérick Barreau, et al., Frontiers in Toxicology 2026. DOI: 10.3389/ftox.2026.1839932

Exclusive enteral nutrition containing transforming growth factor‐β improves intestinal barrier function in a colitis mouse model. Kawthar Boumessid, Vickie Lacroix, ..., Frédérick Barreau, Emmanuel Mas, Journal of Pediatric Gastroenterology and Nutrition 2026. DOI: 10.1002/jpn3.70517

Fast-growing intracellular Mycobacterium tuberculosis populations evade antibiotic treatment. Nathan Day, Baptiste Pradel, ..., Julien Vaubourgeix, et al., Nature Communications 2026. DOI: 10.1038/s41467-026-75915-8

Bidirectional associations between biological aging, cardiovascular health, and cardiovascular risk: findings from the INSPIRE-T lifespan cohort. Mathilde Strumia, Vanina Bongard, ..., Nathalie Vergnolle, Jean‐Paul Motta, ..., Céline Deraison, Chrystelle Bonnart, et al., GeroScience 2026. DOI: 10.1007/s11357-026-02251-6

Accelerated Epigenetic and Inflammatory Aging and Intrinsic Capacity. Laure Rouch, Philipe de Souto Barreto, ..., Nathalie Vergnolle, Jean‐Paul Motta, ..., Céline Deraison, Chrystelle Bonnart, et al., JAMA Network Open 2026. DOI: 10.1001/jamanetworkopen.2026.24102

Perinatal exposure to nano-polystyrene: deleterious imprinting on inflammatory bowel diseases. Melvin Airaud, Amandine Roldan, ..., Lisa Isoard, ..., Sandrine Ménard, Frédérick Barreau, Particle and Fibre Toxicology 2026. DOI: 10.1186/s12989-026-00700-w

Advancing long-read nanopore genome assembly and accurate variant calling for rare disease detection. Shloka Negi, Sarah L. Stenton, ..., Jean Monlong, et al., The American Journal of Human Genetics 2025. DOI: 10.1016/j.ajhg.2025.01.002

Outer Membrane Vesicles as a Versatile Platform for Vaccine Development: Engineering Strategies, Applications and Challenges. Asja Garling, Frédéric Auvray, ..., Éric Oswald, Priscilla Branchu, Journal of Extracellular Vesicles 2025. DOI: 10.1002/jev2.70150

Main genetic factors associated with inflammatory bowel diseases and their consequences on intestinal permeability: involvement in gut inflammation. Arthur Mauduit, Emmanuel Mas, ..., Sandrine Ménard, Frédérick Barreau, Journal of Gastroenterology 2025. DOI: 10.1007/s00535-025-02289-x

Zoonotic potential of uropathogenic Escherichia coli lineages from companion animals. Nicolas Jousserand, Frédéric Auvray, ..., Éric Oswald, Veterinary Research 2025. DOI: 10.1186/s13567-025-01493-0

Uncovering a new family of conserved virulence factors that promote the production of host‐damaging outer membrane vesicles in Gram‐negative bacteria. Audrey Goman, Bérengère Ize, ..., Frédéric Taïeb, ..., Laure David, ..., Priscilla Branchu, Éric Oswald, Journal of Extracellular Vesicles 2025. DOI: 10.1002/jev2.70032

Deciphering the interplay between biology and physics with a finite element method-implemented vertex organoid model: A tool for the mechanical analysis of cell behavior on a spherical organoid shell. Julien Laussu, Déborah Michel, ..., Frédérick Barreau, Emmanuel Mas, et al., PLOS Computational Biology 2025. DOI: 10.1371/journal.pcbi.1012681

Development of intimin-enriched outer membrane vesicles (OMVs) as a vaccine to control intestinal carriage of Enterohemorrhagic Escherichia coli. Asja Garling, Cécile Goursat, ..., Jean‐Philippe Nougayrède, Éric Oswald, Frédéric Auvray, Priscilla Branchu, Vaccine 2025. DOI: 10.1016/j.vaccine.2025.126899

Pharmacology of Intestinal Inflammation and Repair. Céline Deraison, Nathalie Vergnolle, Annual Review of Pharmacology and Toxicology 2025. DOI: 10.1146/annurev-pharmtox-051921-084536

Rethinking the role of animals in antimicrobial resistance. Elissa Khamisse, Xavier Bertrand, et al., The Lancet Microbe 2025. DOI: 10.1016/j.lanmic.2025.101248

Bispecific nanobody® as a new pharmacological drug for the selective inhibition of Trypsin‐3. Mélissa David, Anaïs Faihy, ..., Anissa Edir, ..., Nathalie Vergnolle, ..., Céline Deraison, British Journal of Pharmacology 2025. DOI: 10.1111/bph.70100

Evolution of hepatobiliary involvement in cystic fibrosis children on CFTR modulators. Mélanie Auvray, Nolwenn Laborde, ..., Frédérick Barreau, ..., Emmanuel Mas, Journal of Cystic Fibrosis 2025. DOI: 10.1016/j.jcf.2025.05.003

Comparative analysis of dietary iron deprivation and supplementation in a murine model of colitis. Thanina Medjbeur, Ugo Sardo, ..., Léon Kautz, FASEB BioAdvances 2025. DOI: 10.1096/fba.2025-00022

Pathogenicity of commensal gut biofilm in prefrail aging. Guillaume Le Cosquer, Melissa Pannier, ..., Céline Deraison, Nathalie Vergnolle, Jean‐Paul Motta, et al., npj Biofilms and Microbiomes 2025. DOI: 10.1038/s41522-025-00716-8

Oral indomethacin modifies small intestine biofilms and host-microbe interaction mediators. Arezoo Haghighi, András S. Tóth, ..., Jean‐Paul Motta, Nathalie Vergnolle, et al., Life Sciences 2025. DOI: 10.1016/j.lfs.2025.124114

Differences in maternal diet fiber content influence patterns of gene expression and chromatin accessibility in fetuses and piglets. Smahane Chalabi, Linda M. P. Loonen, ..., Sarah Djebali, et al., Genomics 2025. DOI: 10.1016/j.ygeno.2025.110995

Polygenic risk score prediction accuracy convergence. Léo Henches, Jihye Kim, ..., Arthur Frouin, ..., Sarah Djebali, et al., Human Genetics and Genomics Advances 2025. DOI: 10.1016/j.xhgg.2025.100457

Ablation of Hepatocyte Derived‐FGL1 Does Not Aggravate Metabolic Dysfunction‐Associated Steatotic Liver Disease. Jean Personnaz, Lisa Cannizzo, ..., Aurore Desquesnes, ..., Léon Kautz, The FASEB Journal 2025. DOI: 10.1096/fj.202501997r

Modeling Postoperative Pathologic Ileus in Mice: A Simplified and Translational Approach. Romain Gauthier, Julie Thevenin, ..., Nathalie Vergnolle, ..., Céline Deraison, Neurogastroenterology & Motility 2025. DOI: 10.1111/nmo.70157

Studying Pseudomonas aeruginosa pathogenesis: the need for more than just the PAO1 strain. Laure David, Audrey Goman, ..., Frédéric Taïeb, Priscilla Branchu, Éric Oswald, Microbiology Spectrum 2025. DOI: 10.1128/spectrum.00665-25

Kinetics of molecular patterns captured by mannose-binding lectin in septic shock correlate with clinical outcome: a monocentric prospective observational study. A. Bicart-See, Fanny Vardon‐Bounes, ..., Éric Oswald, Intensive Care Medicine Experimental 2025. DOI: 10.1186/s40635-025-00832-x

Evaluation of the prebiotic potential of polyphenol-rich plant extracts in a mouse model of colitis. Damien Guillemet, Perrine Rousset, ..., Anissa Edir, ..., Laura Guiraud, Nathalie Vergnolle, Jean‐Paul Motta, Microbiota and Host 2025. DOI: 10.1530/mah-25-0007

Preadipocyte IL-13/IL-13Rα1 signaling regulates beige adipogenesis through modulation of PPARγ activity. Alexandra R Yesian, Mayer M. Chalom, ..., Jean Personnaz, et al., Journal of Clinical Investigation 2025. DOI: 10.1172/jci169152

AKT-mediated phosphorylation of TSC2 controls stimulus- and tissue-specific mTORC1 signaling and organ growth. Yann Cormerais, S. Lapp, ..., Jean Personnaz, et al., Developmental Cell 2025. DOI: 10.1016/j.devcel.2025.05.008

Humans as a potential reservoir for the emerging ST301 Shiga toxin-producing Escherichia coli clones of serotype O80:H2?. Frédéric Auvray, Federica Gigliucci, ..., Éric Oswald, Clinical Microbiology and Infection 2025. DOI: 10.1016/j.cmi.2025.05.018

Bacterial nanoparticles as a potent and safe alternative to BCG for bladder cancer immunotherapy. Marine Colson, Arthur Aubry, ..., Éric Oswald, Laure David, Cancer Gene Therapy 2025. DOI: 10.1038/s41417-025-00984-8

Human fallopian tube organoids provide a favourable environment for sperm motility. Nicolas Gatimel, G. Perez, ..., Céline Deraison, Jean‐Paul Motta, ..., Nathalie Vergnolle, Human Reproduction 2025. DOI: 10.1093/humrep/deae258

Proteases in intestinal health and disease. Céline Deraison, Nathalie Vergnolle, Nature Reviews Gastroenterology & Hepatology 2025. DOI: 10.1038/s41575-025-01129-w

Proteolytic bacteria expansion during colitis amplifies inflammation through cleavage of the external domain of PAR2. L Rondeau, B Barbosa da Luz, ..., Céline Deraison, ..., Nathalie Vergnolle, et al., Gut Microbes 2024. DOI: 10.1080/19490976.2024.2387857

Intestinal organoids to model Salmonella infection and its impact on progenitors. Yan Jin, Claire Racaud‐Sultan, ..., Anissa Edir, ..., Nathalie Vergnolle, Agnès Wiedemann, Scientific Reports 2024. DOI: 10.1038/s41598-024-65485-4

Gut microb-aging and its relevance to frailty aging. Guillaume Le Cosquer, Nathalie Vergnolle, Jean‐Paul Motta, Microbes and Infection 2024. DOI: 10.1016/j.micinf.2024.105309

Human colonic organoids for understanding early events of familial adenomatous polyposis pathogenesis. Nolwenn Laborde, Alexandre Barusseaud, ..., Nathalie Vergnolle, ..., Frédérick Barreau, Claire Racaud‐Sultan, Emmanuel Mas, The Journal of Pathology 2024. DOI: 10.1002/path.6366

Mapping the scientific output of organoids for animal and human modeling infectious diseases: a bibliometric assessment. Yan Jin, Jean Monlong, ..., Agnès Wiedemann, Veterinary Research 2024. DOI: 10.1186/s13567-024-01333-7

A human anti-matriptase-2 antibody limits iron overload, α-globin aggregates, and splenomegaly in β-thalassemic mice. Matthew Wake, Anaïs Palin, Audrey Belot, Mathieu Berger, ..., Céline Besson‐Fournier, Chloé Latour, ..., Hélène Coppin, Marie‐Paule Roth, ..., Delphine Meynard, Blood Advances 2024. DOI: 10.1182/bloodadvances.2023012010

Chymotrypsin activity signals to intestinal epithelium by protease‐activated receptor‐dependent mechanisms. Simon Guignard, Mahmoud Saifeddine, ..., Laura Guiraud, ..., Anissa Edir, ..., Nathalie Vergnolle, ..., Céline Deraison, Chrystelle Bonnart, British Journal of Pharmacology 2024. DOI: 10.1111/bph.16341

Fibrinogen‐like 1: A hepatokine linking liver physiology to hematology. Jean Personnaz, Hervé Guillou, Léon Kautz, HemaSphere 2024. DOI: 10.1002/hem3.115

FGL1, une nouvelle cible pour le traitement de l’anémie ?. Thanina Medjbeur, Jean Personnaz, Léon Kautz, médecine/sciences 2024. DOI: 10.1051/medsci/2024123

The hepatokine FGL1 regulates hepcidin and iron metabolism during anemia in mice by antagonizing BMP signaling. Ugo Sardo, Prunelle Perrier, ..., Jean Personnaz, Thanina Medjbeur, Aurore Desquesnes, Lisa Cannizzo, ..., Julie Thevenin, ..., Léon Kautz, Blood 2024. DOI: 10.1182/blood.2023022724

Cold-induced thermogenesis requires neutral-lipase-mediated intracellular lipolysis in brown adipocytes. Étienne Mouisel, A Bodon, ..., Stéphanie Cassant‐Sourdy, et al., Cell Metabolism 2024. DOI: 10.1016/j.cmet.2024.10.018

S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis. Liwen Deng, Flavia G. Costa, ..., Céline Deraison, ..., Nathalie Vergnolle, et al., Cell 2023. DOI: 10.1016/j.cell.2023.10.019

Prevalence and characterization of the seven major serotypes of Shiga toxin-producing Escherichia coli (STEC) in veal calves slaughtered in France. Frédéric Auvray, Clémence Bièche-Terrier, ..., Éric Oswald, et al., Veterinary Microbiology 2023. DOI: 10.1016/j.vetmic.2023.109754

Oxygen concentration modulates colibactin production. Nadège Bossuet‐Greif, Cécile Guyonnet, ..., Priscilla Branchu, Éric Oswald, Jean‐Philippe Nougayrède, Gut Microbes 2023. DOI: 10.1080/19490976.2023.2222437

HlyF, an underestimated virulence factor of uropathogenic Escherichia coli. Camille V. Chagneau, Delphine Payros, ..., Priscilla Branchu, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, Clinical Microbiology and Infection 2023. DOI: 10.1016/j.cmi.2023.07.024

TAGADA: a scalable pipeline to improve genome annotations with RNA-seq data. Cyril Kurylo, Cervin Guyomar, ..., Sarah Djebali, NAR Genomics and Bioinformatics 2023. DOI: 10.1093/nargab/lqad089

Enhancer/gene relationships: Need for more reliable genome-wide reference sets. Tristan Hoellinger, Camille Mestre, ..., Sarah Djebali, Frontiers in Bioinformatics 2023. DOI: 10.3389/fbinf.2023.1092853

PaintorPipe: a pipeline for genetic variant fine-mapping using functional annotations. Zoé Gerber, Michel Fisun, ..., Sarah Djebali, Bioinformatics Advances 2023. DOI: 10.1093/bioadv/vbad188

A draft human pangenome reference. Wen‐Wei Liao, Mobin Asri, ..., Jean Monlong, et al., Nature 2023. DOI: 10.1038/s41586-023-05896-x

Pangenome graph construction from genome alignments with Minigraph-Cactus. Glenn Hickey, Jean Monlong, et al., Nature Biotechnology 2023. DOI: 10.1038/s41587-023-01793-w

Scalable Nanopore sequencing of human genomes provides a comprehensive view of haplotype-resolved variation and methylation. Mikhail Kolmogorov, Kimberley J. Billingsley, ..., Jean Monlong, et al., Nature Methods 2023. DOI: 10.1038/s41592-023-01993-x

From ribosome to ribotoxins: understanding the toxicity of deoxynivalenol and Shiga toxin, two food borne toxins. Marion Garofalo, Delphine Payros, Frédéric Taïeb, ..., Jean‐Philippe Nougayrède, et al., Critical Reviews in Food Science and Nutrition 2023. DOI: 10.1080/10408398.2023.2271101

Outer membrane vesicles produced by pathogenic strains of Escherichia coli block autophagic flux and exacerbate inflammasome activation. Laure David, Frédéric Taïeb, ..., Éric Oswald, Autophagy 2022. DOI: 10.1080/15548627.2022.2054040

Cross-Talk Between the Intestinal Epithelium and Salmonella Typhimurium. Sandrine Ménard, Sonia Lacroix‐Lamandé, ..., Agnès Wiedemann, Frontiers in Microbiology 2022. DOI: 10.3389/fmicb.2022.906238

Identification of bacterial lipopeptides as key players in IBS. Camille Petitfils, Sarah Maurel, ..., Frédéric Auvray, ..., Jean‐Paul Motta, ..., Éric Oswald, et al., Gut 2022. DOI: 10.1136/gutjnl-2022-328084

A novel toxic effect of foodborne trichothecenes: The exacerbation of genotoxicity. Marion Garofalo, Delphine Payros, ..., Éric Oswald, Jean‐Philippe Nougayrède, et al., Environmental Pollution 2022. DOI: 10.1016/j.envpol.2022.120625

Wild Boars as Reservoir of Highly Virulent Clone of Hybrid Shiga Toxigenic and Enterotoxigenic Escherichia coli Responsible for Edema Disease, France. Alexandre Perrat, Priscilla Branchu, ..., Frédéric Auvray, Éric Oswald, Emerging Infectious Diseases 2022. DOI: 10.3201/eid2802.211491

Uncoupling the Hsp90 and DnaK chaperone activities revealed the in vivo relevance of their collaboration in bacteria. Marie Corteggiani, Nadège Bossuet‐Greif, Jean‐Philippe Nougayrède, ..., Éric Oswald, et al., Proceedings of the National Academy of Sciences 2022. DOI: 10.1073/pnas.2201779119

Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptor. Jean Personnaz, Enzo Piccolo, et al., Science Advances 2022. DOI: 10.1126/sciadv.abg9055

The pks island: a bacterial Swiss army knife? Colibactin: beyond DNA damage and cancer. Camille V. Chagneau, Delphine Payros, ..., Frédéric Auvray, Jean‐Philippe Nougayrède, Éric Oswald, Trends in Microbiology 2022. DOI: 10.1016/j.tim.2022.05.010

Respiratory syncytial virus ribonucleoproteins hijack microtubule Rab11 dependent transport for intracellular trafficking. Gina Cosentino, Katherine Marougka, Aurore Desquesnes, et al., PLOS Pathogens 2022. DOI: 10.1371/journal.ppat.1010619

Diagnosis, Management, and Prevention of Button Battery Ingestion in Childhood. Amani Mubarak, Marc A. Benninga, ..., Emmanuel Mas, et al., Journal of Pediatric Gastroenterology and Nutrition 2021. DOI: 10.1097/mpg.0000000000003048

Effects of Hydrogen Sulfide on the Microbiome: From Toxicity to Therapy. André G. Buret, Thibault Allain, Jean‐Paul Motta, et al., Antioxidants & Redox Signaling 2021. DOI: 10.1089/ars.2021.0004

A Toxic Friend: Genotoxic and Mutagenic Activity of the Probiotic Strain Escherichia coli Nissle 1917. Jean‐Philippe Nougayrède, Camille V. Chagneau, Jean‐Paul Motta, ..., Frédéric Taïeb, ..., Éric Oswald, mSphere 2021. DOI: 10.1128/msphere.00624-21

Insights into evolution and coexistence of the colibactin- and yersiniabactin secondary metabolite determinants in enterobacterial populations. Haleluya Wami, Alexander Wallenstein, ..., Éric Oswald, et al., Microbial Genomics 2021. DOI: 10.1099/mgen.0.000577

Uropathogenic E. coli induces DNA damage in the bladder. Camille V. Chagneau, Clémence Massip, ..., Jean‐Paul Motta, ..., Marie‐Paule Roth, Hélène Coppin, ..., Jean‐Philippe Nougayrède, Éric Oswald, PLOS Pathogens 2021. DOI: 10.1371/journal.ppat.1009310

Adipose-Derived Stem Cells in the Treatment of Perianal Fistulas in Crohn’s Disease: Rationale, Clinical Results and Perspectives. Étienne Buscail, Guillaume Le Cosquer, ..., Céline Deraison, Nathalie Vergnolle, et al., International Journal of Molecular Sciences 2021. DOI: 10.3390/ijms22189967

Pangenomics enables genotyping of known structural variants in 5202 diverse genomes. Jouni Sirén, Jean Monlong, et al., Science 2021. DOI: 10.1126/science.abg8871

SHP2 drives inflammation-triggered insulin resistance by reshaping tissue macrophage populations. Romain Paccoud, Céline Saint-Laurent, ..., Jean Personnaz, et al., Science Translational Medicine 2021. DOI: 10.1126/scitranslmed.abe2587

Multiform antimicrobial resistance from a metabolic mutation. Sarah Schrader, Hélène Botella, ..., Julien Vaubourgeix, Science Advances 2021. DOI: 10.1126/sciadv.abh2037

A condensate-hardening drug blocks RSV replication in vivo. Jennifer Risso-Ballester, Marie Galloux, ..., Aurore Desquesnes, et al., Nature 2021. DOI: 10.1038/s41586-021-03703-z

Expanded encyclopaedias of DNA elements in the human and mouse genomes. Federico Abascal, Reyes Acosta, ..., Sarah Djebali, et al., Nature 2020. DOI: 10.1038/s41586-020-2493-4

Genotyping structural variants in pangenome graphs using the vg toolkit. Glenn Hickey, David N. Heller, Jean Monlong, et al., Genome Biology 2020. DOI: 10.1186/s13059-020-1941-7

A fully human anti-BMP6 antibody reduces the need for erythropoietin in rodent models of the anemia of chronic disease. Verena Petzer, Piotr Tymoszuk, ..., Léon Kautz, et al., Blood 2020. DOI: 10.1182/blood.2019004653

Bacteria-derived long chain fatty acid exhibits anti-inflammatory properties in colitis. Julien Pujo, Camille Petitfils, ..., Frédérick Barreau, ..., Éric Oswald, et al., Gut 2020. DOI: 10.1136/gutjnl-2020-321173

The Genotoxin Colibactin Shapes Gut Microbiota in Mice. Sophie Tronnet, Pauline Floch, ..., Éric Oswald, mSphere 2020. DOI: 10.1128/msphere.00589-20

Psychological Stress, Intestinal Barrier Dysfunctions, and Autoimmune Disorders: An Overview. Hanna Ilchmann-Diounou, Sandrine Ménard, Frontiers in Immunology 2020. DOI: 10.3389/fimmu.2020.01823

Characterization of Human Colon Organoids From Inflammatory Bowel Disease Patients. Emilie d'Aldebert, Muriel Quaranta, ..., Claire Racaud‐Sultan, Emmanuel Mas, Céline Deraison, Nathalie Vergnolle, Frontiers in Cell and Developmental Biology 2020. DOI: 10.3389/fcell.2020.00363

Biology of antimicrobial resistance and approaches to combat it. Sarah Schrader, Julien Vaubourgeix, et al., Science Translational Medicine 2020. DOI: 10.1126/scitranslmed.aaz6992

Nonredundant functions of Mycobacterium tuberculosis chaperones promote survival under stress. Alexa P. Harnagel, Landys Lopez Quezada, ..., Julien Vaubourgeix, et al., Molecular Microbiology 2020. DOI: 10.1111/mmi.14615

Multi-species annotation of transcriptome and chromatin structure in domesticated animals. Sylvain Foissac, Sarah Djebali, et al., BMC Biology 2019. DOI: 10.1186/s12915-019-0726-5

A variant erythroferrone disrupts iron homeostasis in SF3B1 -mutated myelodysplastic syndrome. Sabrina Bondu, Anne‐Sophie Alary, ..., Léon Kautz, et al., Science Translational Medicine 2019. DOI: 10.1126/scitranslmed.aav5467

Deciphering the interplay between the genotoxic and probiotic activities of Escherichia coli Nissle 1917. Clémence Massip, Priscilla Branchu, ..., Jean‐Philippe Nougayrède, Éric Oswald, PLOS Pathogens 2019. DOI: 10.1371/journal.ppat.1008029

Vegan diet in children and adolescents. Recommendations from the French-speaking Pediatric Hepatology, Gastroenterology and Nutrition Group (GFHGNP). Julie Lemale, Emmanuel Mas, et al., Archives de Pédiatrie 2019. DOI: 10.1016/j.arcped.2019.09.001

Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition. Elaine Ballinger, John Mosior, ..., Julien Vaubourgeix, et al., Science 2019. DOI: 10.1126/science.aau8959

Intestinal Bile Acids Induce a Morphotype Switch in Vancomycin-Resistant Enterococcus that Facilitates Intestinal Colonization. Peter T. McKenney, Jinyuan Yan, Julien Vaubourgeix, et al., Cell Host & Microbe 2019. DOI: 10.1016/j.chom.2019.03.008

Persistent Mycobacterium tuberculosis infection in mice requires PerM for successful cell division. Ruojun Wang, Kaj M. Kreutzfeldt, ..., Julien Vaubourgeix, et al., eLife 2019. DOI: 10.7554/elife.49570

Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2. Alberto Caminero, Justin L. McCarville, ..., Céline Deraison, ..., Nathalie Vergnolle, et al., Nature Communications 2019. DOI: 10.1038/s41467-019-09037-9

House dust mites activate nociceptor–mast cell clusters to drive type 2 skin inflammation. Nadine Serhan, Lilian Basso, ..., Chrystelle Bonnart, et al., Nature Immunology 2019. DOI: 10.1038/s41590-019-0493-z

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics. Alvaro Barbeira, Scott Dickinson, ..., Jean Monlong, et al., Nature Communications 2018. DOI: 10.1038/s41467-018-03621-1

Shift in skin microbiota of Western European women across aging. Romain Jugé, Pauline Rouaud, ..., Marie‐Paule Roth, Hélène Coppin, et al., Journal of Applied Microbiology 2018. DOI: 10.1111/jam.13929

Erythroferrone is not required for the glucoregulatory and hematologic effects of chronic erythropoietin treatment in mice. Richard Coffey, Ugo Sardo, Léon Kautz, et al., Physiological Reports 2018. DOI: 10.14814/phy2.13890

The Colibactin Genotoxin Generates DNA Interstrand Cross-Links in Infected Cells. Nadège Bossuet‐Greif, Julien Vignard, Frédéric Taïeb, ..., Éric Oswald, Jean‐Philippe Nougayrède, mBio 2018. DOI: 10.1128/mbio.02393-17

NOD2 Expression in Intestinal Epithelial Cells Protects Toward the Development of Inflammation and Associated Carcinogenesis. Audrey Ferrand, Ziad Al Nabhani, ..., Emmanuel Mas, ..., Frédérick Barreau, Cellular and Molecular Gastroenterology and Hepatology 2018. DOI: 10.1016/j.jcmgh.2018.10.009

Diagnostic Yield of Next-generation Sequencing in Very Early-onset Inflammatory Bowel Diseases: A Multicentre Study. Fabienne Charbit‐Henrion, Marianna Parlato, ..., Emmanuel Mas, et al., Journal of Crohn's and Colitis 2018. DOI: 10.1093/ecco-jcc/jjy068

Targeting the Proteostasis Network for Mycobacterial Drug Discovery. Tania J. Lupoli, Julien Vaubourgeix, et al., ACS Infectious Diseases 2018. DOI: 10.1021/acsinfecdis.7b00231

Building Walls: Work That Never Ends. Hélène Botella, Julien Vaubourgeix, Trends in Microbiology 2018. DOI: 10.1016/j.tim.2018.11.006

An atlas of human long non-coding RNAs with accurate 5′ ends. Chung-Chau Hon, Jordan A. Ramilowski, ..., Sarah Djebali, et al., Nature 2017. DOI: 10.1038/nature21374

Deletion of BMP6 worsens the phenotype of HJV-deficient mice and attenuates hepcidin levels reached after LPS challenge. Chloé Latour, Céline Besson‐Fournier, ..., Delphine Meynard, Marie‐Paule Roth, Hélène Coppin, Blood 2017. DOI: 10.1182/blood-2017-07-795658

Immunoassay for human serum erythroferrone. Tomas Ganz, Grace Jung, ..., Léon Kautz, et al., Blood 2017. DOI: 10.1182/blood-2017-04-777987

Erythroferrone and matriptase‐2 independently regulate hepcidin expression. Sharraya Aschemeyer, Victoria Gabayan, ..., Léon Kautz, American Journal of Hematology 2017. DOI: 10.1002/ajh.24672

Identification of an analgesic lipopeptide produced by the probiotic Escherichia coli strain Nissle 1917. Teresa Pérez, Julien Pujo, ..., Frédérick Barreau, ..., Éric Oswald, et al., Nature Communications 2017. DOI: 10.1038/s41467-017-01403-9

The Food Contaminant Deoxynivalenol Exacerbates the Genotoxicity of Gut Microbiota. Delphine Payros, Ulrich Dobrindt, ..., Éric Oswald, et al., mBio 2017. DOI: 10.1128/mbio.00007-17

Nod2: The intestinal gate keeper. Ziad Al Nabhani, Gilles Dietrich, ..., Frédérick Barreau, PLOS Pathogens 2017. DOI: 10.1371/journal.ppat.1006177

Mycobacterium tuberculosis protease MarP activates a peptidoglycan hydrolase during acid stress. Hélène Botella, Julien Vaubourgeix, et al., The EMBO Journal 2017. DOI: 10.15252/embj.201695028

Distinct Spatiotemporal Dynamics of Peptidoglycan Synthesis between Mycobacterium smegmatis and Mycobacterium tuberculosis. Hélène Botella, Guangli Yang, ..., Julien Vaubourgeix, mBio 2017. DOI: 10.1128/mbio.01183-17

Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death. Laure Botella, Julien Vaubourgeix, et al., Nature Communications 2017. DOI: 10.1038/ncomms14731

Protectin D1 n-3 DPA and resolvin D5 n-3 DPA are effectors of intestinal protection. Thomas Gobbetti, Jesmond Dalli, ..., Nathalie Vergnolle, Céline Deraison, et al., Proceedings of the National Academy of Sciences 2017. DOI: 10.1073/pnas.1617290114

Epithelial expression and function of trypsin-3 in irritable bowel syndrome. Claire Rolland-Fourcade, Alexandre Denadai‐Souza, ..., Jean‐Paul Motta, ..., Céline Deraison, Nathalie Vergnolle, Gut 2017. DOI: 10.1136/gutjnl-2016-312094

Giardia duodenalis induces pathogenic dysbiosis of human intestinal microbiota biofilms. Jennifer Beatty, Sarah Akierman, Jean‐Paul Motta, et al., International Journal for Parasitology 2017. DOI: 10.1016/j.ijpara.2016.11.010

Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism. Thomas Farge, Estelle Saland, ..., Stéphanie Cassant‐Sourdy, et al., Cancer Discovery 2017. DOI: 10.1158/2159-8290.cd-16-0441

Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice. Antonella Nai, Aude Rubio, ..., Chloé Latour, Céline Besson‐Fournier, ..., Hélène Coppin, ..., Delphine Meynard, Blood 2016. DOI: 10.1182/blood-2015-11-681494

Hepcidin upregulation by inflammation is independent of Smad1/5/8 signaling by activin B. Céline Besson‐Fournier, Aurélie Gineste, Chloé Latour, ..., Delphine Meynard, ..., Éric Oswald, Hélène Coppin, Marie‐Paule Roth, Blood 2016. DOI: 10.1182/blood-2016-10-748541

The Enterobacterial Genotoxins: Cytolethal Distending Toxin and Colibactin. Frédéric Taïeb, C. Petit, Jean‐Philippe Nougayrède, Éric Oswald, EcoSal Plus 2016. DOI: 10.1128/ecosalplus.esp-0008-2016

The Intestinal Microenvironment and Functional Gastrointestinal Disorders. Giovanni Barbara, Christine Feinle‐Bisset, ..., Nathalie Vergnolle, et al., Gastroenterology 2016. DOI: 10.1053/j.gastro.2016.02.028

Retrograde Trafficking Inhibitor of Shiga Toxins Reduces Morbidity and Mortality of Mice Infected with Enterohemorrhagic Escherichia coli. Thomas Sécher, Ayaka Shima, ..., Éric Oswald, Antimicrobial Agents and Chemotherapy 2015. DOI: 10.1128/aac.00455-15

Stressed Mycobacteria Use the Chaperone ClpB to Sequester Irreversibly Oxidized Proteins Asymmetrically Within and Between Cells. Julien Vaubourgeix, Gang Lin, et al., Cell Host & Microbe 2015. DOI: 10.1016/j.chom.2014.12.008

Disruption of an M. tuberculosis Membrane Protein Causes a Magnesium-dependent Cell Division Defect and Failure to Persist in Mice. Nichole Goodsmith, Xinzheng V. Guo, ..., Julien Vaubourgeix, et al., PLOS Pathogens 2015. DOI: 10.1371/journal.ppat.1004645

The Genotoxin Colibactin Exacerbates Lymphopenia and Decreases Survival Rate in Mice Infected With Septicemic Escherichia coli. Ingrid Marcq, Pascal Martin, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, Journal of Infectious Diseases 2014. DOI: 10.1093/infdis/jiu071

Interplay between Siderophores and Colibactin Genotoxin Biosynthetic Pathways in Escherichia coli. Patricia Martín, Ingrid Marcq, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, PLoS Pathogens 2013. DOI: 10.1371/journal.ppat.1003437

N,C-Capped Dipeptides with Selectivity for Mycobacterial Proteasome over Human Proteasomes: Role of S3 and S1 Binding Pockets. Gang Lin, Tamutenda Chidawanyika, ..., Julien Vaubourgeix, et al., Journal of the American Chemical Society 2013. DOI: 10.1021/ja400021x

A Common Mechanism of Inhibition of the Mycobacterium tuberculosis Mycolic Acid Biosynthetic Pathway by Isoxyl and Thiacetazone. Anna E. Grzegorzewicz, Jana Korduláková, ..., Julien Vaubourgeix, et al., Journal of Biological Chemistry 2012. DOI: 10.1074/jbc.m112.400994

Deciphering sulfoglycolipids of Mycobacterium tuberculosis. Emilie Layre, D. Cala-De Paepe, ..., Julien Vaubourgeix, et al., Journal of Lipid Research 2011. DOI: 10.1194/jlr.m013482

Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells. Gabriel Cuevas‐Ramos, C. Petit, ..., Éric Oswald, Jean‐Philippe Nougayrède, Proceedings of the National Academy of Sciences 2010. DOI: 10.1073/pnas.1001261107

Pathogenic Bacteria Target NEDD8-Conjugated Cullins to Hijack Host-Cell Signaling Pathways. Grégory Jubelin, Frédéric Taïeb, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, PLoS Pathogens 2010. DOI: 10.1371/journal.ppat.1001128

Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ. Jichan Jang, Alexandre Stella, ..., Julien Vaubourgeix, et al., Microbiology 2010. DOI: 10.1099/mic.0.038133-0

S-Adenosyl-N-decyl-aminoethyl, a Potent Bisubstrate Inhibitor of Mycobacterium tuberculosis Mycolic Acid Methyltransferases. Julien Vaubourgeix, F. Bardou, et al., Journal of Biological Chemistry 2009. DOI: 10.1074/jbc.m809599200

Foamy Macrophages from Tuberculous Patients’ Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence. Pascale Peyron, Julien Vaubourgeix, et al., PLoS Pathogens 2008. DOI: 10.1371/journal.ppat.1000204

Escherichia coli Induces DNA Double-Strand Breaks in Eukaryotic Cells. Jean‐Philippe Nougayrède, Stefan Homburg, Frédéric Taïeb, ..., Éric Oswald, Science 2006. DOI: 10.1126/science.1127059

Role of Tir and Intimin in the Virulence of Rabbit EnteropathogenicEscherichia coliSerotype O103:H2. Olivier Marchès, Jean‐Philippe Nougayrède, ..., Éric Oswald, Infection and Immunity 2000. DOI: 10.1128/iai.68.4.2171-2182.2000

A new cytolethal distending toxin (CDT) from Escherichia coli producing CNF2 blocks HeLa cell division in G2/M phase. Sylvie Pérès, Olivier Marchès, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, Molecular Microbiology 1997. DOI: 10.1046/j.1365-2958.1997.4181785.x