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POSTDOCTORANTE

POSTDOCTORAL Fellow

CONTACTS

​​00 33 (0)5 62 74 45 73

EQUIPE 6 INTERACTIONS ENTRE L'ENVIRONNEMENT ET L'ÉPITHÉLIUM INTESTINAL
TEAM 6 ENVIRONMENT & INTESTINAL EPITHELIUM INTERACTIONS

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Mini CV

expertise

EDUCATION

• 2016-  PhD degre  Pharmacology - Université Paul Sabatier - Toulouse, France.
• 2012   Master degree  Pharmacology - Université Paul Sabatier - Toulouse, France.    

 
PROFESSIONAL EXPERIENCE

• 2019-Present  Post-doctoral fellow - Digestive Health Research Institut (IRSD, INSERM) -Toulouse, France.
• 2017-2019       Project leader in analytical chemistry - Antellis - Toulouse, France.​

• Cell culture / organoid culture
• BRET
• Signal transduction study (proteomic and transcriptomic)
• Microscopy (confocal)
• Analytical chemistry

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Recherche/projet  research/project

Impact of extracellular matrix alteration in the initiation of colorectal cancer
 

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Production scientifique scientific production 

1: G protein stoichiometry dictates biased agonism through distinct receptor-G protein partitioning.
Onfroy L, Galandrin S, Pontier SM, Seguelas MH, N'Guyen D, Sénard JM, Galés C.  Sci Rep. 2017 Aug 11;7(1):7885. doi: 10.1038/s41598-017-07392-5. PubMed PMID: 28801617; PubMed Central PMCID: PMC5554226.

2: Delineating biased ligand efficacy at 7TM receptors from an experimental perspective. 
Galandrin S, Onfroy L, Poirot MC, Sénard JM, Galés C. Int J Biochem Cell Biol. 2016 Aug;77(Pt B):251-63. doi: 10.1016/j.biocel.2016.04.009. Epub 2016 Apr 21. Review. PubMed PMID: 27107932.

3: Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor Signaling. 
​M'Kadmi C, Leyris JP, Onfroy L, Galés C, Saulière A, Gagne D, Damian M, Mary S, Maingot M, Denoyelle S, Verdié P, Fehrentz JA, Martinez J, Banères JL, Marie J. Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor Signaling. J Biol Chem. 2015 Nov 6;290(45):27021-39. doi: 10.1074/jbc.M115.659250. Epub 2015 Sep 11. PubMed PMID: 26363071; PubMed Central PMCID: PMC4646384.