Jean-Philippe Nougayrede


    Publications

    Bacterial Hsp90 promotes virulence factor production through maintenance of NRPS megaenzymes. Alison Fratacci, Amine Ali Chaouche, ..., Nadège Bossuet‐Greif, ..., Jean‐Philippe Nougayrède, Éric Oswald, et al., bioRxiv 2025. DOI: 10.1101/2025.07.01.662645

    Development of intimin-enriched outer membrane vesicles (OMVs) as a vaccine to control intestinal carriage of Enterohemorrhagic Escherichia coli. Asja Garling, Cécile Goursat, Carine Séguy, ..., Jean‐Philippe Nougayrède, Éric Oswald, Frédéric Auvray, Priscilla Branchu, Vaccine 2025. DOI: 10.1016/j.vaccine.2025.126899

    From ribosome to ribotoxins: understanding the toxicity of deoxynivalenol and Shiga toxin, two food borne toxins. Marion Garofalo, Delphine Payros, Frédéric E. Taieb, Éric Oswald, Jean‐Philippe Nougayrède, et al., Critical Reviews in Food Science and Nutrition 2023. DOI: 10.1080/10408398.2023.2271101

    HlyF, an underestimated virulence factor of uropathogenic Escherichia coli. Camille V. Chagneau, Delphine Payros, ..., Carine Séguy, Clémence Massip, Priscilla Branchu, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, Clinical Microbiology and Infection 2023. DOI: 10.1016/j.cmi.2023.07.024

    Oxygen concentration modulates colibactin production. Nadège Bossuet‐Greif, Cécile Guyonnet, Camille V. Chagneau, ..., Marie Pénary, ..., Priscilla Branchu, Éric Oswald, Jean‐Philippe Nougayrède, Gut Microbes 2023. DOI: 10.1080/19490976.2023.2222437

    A novel toxic effect of foodborne trichothecenes: The exacerbation of genotoxicity. Marion Garofalo, Delphine Payros, Marie Pénary, Éric Oswald, Jean‐Philippe Nougayrède, et al., Environmental Pollution 2022. DOI: 10.1016/j.envpol.2022.120625

    Uncoupling the Hsp90 and DnaK chaperone activities revealed the in vivo relevance of their collaboration in bacteria. Marie Corteggiani, Nadège Bossuet‐Greif, Jean‐Philippe Nougayrède, ..., Éric Oswald, et al., Proceedings of the National Academy of Sciences 2022. DOI: 10.1073/pnas.2201779119

    The pks island: a bacterial Swiss army knife? Colibactin: beyond DNA damage and cancer. Camille V. Chagneau, Delphine Payros, ..., Frédéric Auvray, Jean‐Philippe Nougayrède, Éric Oswald, Trends in Microbiology 2022. DOI: 10.1016/j.tim.2022.05.010

    Two Polyketides Intertwined in Complex Regulation: Posttranscriptional CsrA-Mediated Control of Colibactin and Yersiniabactin Synthesis in Escherichia coli. Nadine Rehm, Alexander Wallenstein, ..., Camille V. Chagneau, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, et al., mBio 2022. DOI: 10.1128/mbio.03814-21

    The foodborne contaminant deoxynivalenol exacerbates DNA damage caused by a broad spectrum of genotoxic agents. Marion Garofalo, Delphine Payros, Éric Oswald, Jean‐Philippe Nougayrède, et al., Science of The Total Environment 2022. DOI: 10.1016/j.scitotenv.2022.153280

    Reply to Dubbert and von Bünau, “A Probiotic Friend”. Jean‐Philippe Nougayrède, Éric Oswald, mSphere 2021. DOI: 10.1128/msphere.00906-21

    Tackling the Threat of Cancer Due to Pathobionts Producing Colibactin: Is Mesalamine the Magic Bullet?. Min Tang-Fichaux, Priscilla Branchu, Jean‐Philippe Nougayrède, Éric Oswald, Toxins 2021. DOI: 10.3390/toxins13120897

    A Toxic Friend: Genotoxic and Mutagenic Activity of the Probiotic Strain Escherichia coli Nissle 1917. Jean‐Philippe Nougayrède, Camille V. Chagneau, Jean‐Paul Motta, Nadège Bossuet‐Greif, ..., Frédéric E. Taieb, ..., Éric Oswald, mSphere 2021. DOI: 10.1128/msphere.00624-21

    Insights into the acquisition of the pks island and production of colibactin in the Escherichia coli population. Frédéric Auvray, Alexandre Perrat, ..., Camille V. Chagneau, Nadège Bossuet‐Greif, Clémence Massip, Hubert Brugère, Jean‐Philippe Nougayrède, ..., Priscilla Branchu, ..., Éric Oswald, Microbial Genomics 2021. DOI: 10.1099/mgen.0.000579

    Uropathogenic E. coli induces DNA damage in the bladder. Camille V. Chagneau, Clémence Massip, Nadège Bossuet‐Greif, ..., Jean‐Paul Motta, ..., Marie‐Paule Roth, Hélène Coppin, ..., Jean‐Philippe Nougayrède, Éric Oswald, PLOS Pathogens 2021. DOI: 10.1371/journal.ppat.1009310

    The Polyphosphate Kinase of Escherichia coli Is Required for Full Production of the Genotoxin Colibactin. Min Tang-Fichaux, Camille V. Chagneau, Nadège Bossuet‐Greif, Jean‐Philippe Nougayrède, Éric Oswald, Priscilla Branchu, mSphere 2020. DOI: 10.1128/msphere.01195-20

    Deciphering the interplay between the genotoxic and probiotic activities of Escherichia coli Nissle 1917. Clémence Massip, Priscilla Branchu, Nadège Bossuet‐Greif, Camille V. Chagneau, ..., Damien Dubois, Jean‐Philippe Nougayrède, Éric Oswald, PLOS Pathogens 2019. DOI: 10.1371/journal.ppat.1008029

    The Colibactin Genotoxin Generates DNA Interstrand Cross-Links in Infected Cells. Nadège Bossuet‐Greif, Julien Vignard, Frédéric E. Taieb, ..., Damien Dubois, ..., Éric Oswald, Jean‐Philippe Nougayrède, mBio 2018. DOI: 10.1128/mbio.02393-17

    The Genotoxin Colibactin Exacerbates Lymphopenia and Decreases Survival Rate in Mice Infected With Septicemic Escherichia coli. Ingrid Marcq, P. Martin, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, Journal of Infectious Diseases 2014. DOI: 10.1093/infdis/jiu071

    Interplay between Siderophores and Colibactin Genotoxin Biosynthetic Pathways in Escherichia coli. Patricia Martín, Ingrid Marcq, ..., Marie Pénary, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, PLoS Pathogens 2013. DOI: 10.1371/journal.ppat.1003437

    Pathogenic Bacteria Target NEDD8-Conjugated Cullins to Hijack Host-Cell Signaling Pathways. Grégory Jubelin, Frédéric E. Taieb, ..., Marie Pénary, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, PLoS Pathogens 2010. DOI: 10.1371/journal.ppat.1001128

    Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells. Gabriel Cuevas Ramos, Claude R. Petit, ..., Éric Oswald, Jean‐Philippe Nougayrède, Proceedings of the National Academy of Sciences 2010. DOI: 10.1073/pnas.1001261107

    Escherichia coli Induces DNA Double-Strand Breaks in Eukaryotic Cells. Jean‐Philippe Nougayrède, Stefan Homburg, Frédéric E. Taieb, ..., Éric Oswald, Science 2006. DOI: 10.1126/science.1127059

    Role of Tir and Intimin in the Virulence of Rabbit EnteropathogenicEscherichia coliSerotype O103:H2. Olivier Marchès, Jean‐Philippe Nougayrède, ..., Éric Oswald, Infection and Immunity 2000. DOI: 10.1128/iai.68.4.2171-2182.2000

    A new cytolethal distending toxin (CDT) from Escherichia coli producing CNF2 blocks HeLa cell division in G2/M phase. Sylvie Y. Pérès, Olivier Marchès, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, Molecular Microbiology 1997. DOI: 10.1046/j.1365-2958.1997.4181785.x