Exclusive enteral nutrition containing transforming growth factor‐β improves intestinal barrier function in a colitis mouse model. Kawthar Boumessid, Vickie Lacroix, ..., Frédérick Barreau, Emmanuel Mas, Journal of Pediatric Gastroenterology and Nutrition 2026. DOI: 10.1002/jpn3.70517

Fast-growing intracellular Mycobacterium tuberculosis populations evade antibiotic treatment. Nathan J. Day, Baptiste Pradel, ..., Julien Vaubourgeix, et al., Nature Communications 2026. DOI: 10.1038/s41467-026-75915-8

Cyclic exclusive enteral nutrition versus partial enteral nutrition to maintain long-term drug-free remission in paediatric Crohn’s disease (CD-HOPE): an open-label, endpoint-blinded, randomised controlled trial. Bénédicte Pigneur, Christine Martinez‐Vinson, ..., Anne Laure Breton, et al., The Lancet Gastroenterology & Hepatology 2026. DOI: 10.1016/s2468-1253(25)00262-6

Intestinal toxicity of functionalized polystyrene nanoplastics in NOD2 models of Crohn’s disease susceptibility. Manon Dussol, Sandrine Ménard, ..., Frédérick Barreau, et al., Frontiers in Toxicology 2026. DOI: 10.3389/ftox.2026.1839932

Mtb-Timer: a fluorescent reporter to visualize Mycobacterium tuberculosis replication and antibiotic responses. Víctor Campo-Pérez, Chak Hon Luk, ..., Julien Vaubourgeix, et al., mSystems 2026. DOI: 10.1128/msystems.01796-25

Comment un mécanisme de résistance aux antibiotiques favorise la virulence bactérienne. Audrey Goman, Lola Manenc, ..., Priscilla Branchu, Éric Oswald, médecine/sciences 2026. DOI: 10.1051/medsci/2025252

Perinatal exposure to nano-polystyrene: deleterious imprinting on inflammatory bowel diseases. Melvin Airaud, Amandine Roldan, ..., Lisa Isoard, ..., Sandrine Ménard, Frédérick Barreau, Particle and Fibre Toxicology 2026. DOI: 10.1186/s12989-026-00700-w

High thrombin activity associated with crohn’s disease induces microbiota pathogenicity contributing to mucosal inflammation. Guillaume Le Cosquer, Melissa Pannier, ..., Laura Guiraud, ..., Perrine Rousset, ..., Étienne Buscail, ..., Céline Deraison, Nathalie Vergnolle, Jean‐Paul Motta, Gut Microbes 2026. DOI: 10.1080/19490976.2026.2687903

Advancing long-read nanopore genome assembly and accurate variant calling for rare disease detection. Shloka Negi, Sarah L. Stenton, ..., Jean Monlong, et al., The American Journal of Human Genetics 2025. DOI: 10.1016/j.ajhg.2025.01.002

AKT-mediated phosphorylation of TSC2 controls stimulus- and tissue-specific mTORC1 signaling and organ growth. Yann Cormerais, Samuel C. Lapp, ..., Jean Personnaz, et al., Developmental Cell 2025. DOI: 10.1016/j.devcel.2025.05.008

Polygenic risk score prediction accuracy convergence. Léo Henches, Jihye Kim, ..., Arthur Frouin, ..., Sarah Djebali, et al., Human Genetics and Genomics Advances 2025. DOI: 10.1016/j.xhgg.2025.100457

Development of intimin-enriched outer membrane vesicles (OMVs) as a vaccine to control intestinal carriage of Enterohemorrhagic Escherichia coli. Asja Garling, Cécile Goursat, Carine Séguy, ..., Jean‐Philippe Nougayrède, Éric Oswald, Frédéric Auvray, Priscilla Branchu, Vaccine 2025. DOI: 10.1016/j.vaccine.2025.126899

Preadipocyte IL-13/IL-13Rα1 signaling regulates beige adipogenesis through modulation of PPARγ activity. Alexandra R Yesian, Mayer M. Chalom, ..., Jean Personnaz, et al., Journal of Clinical Investigation 2025. DOI: 10.1172/jci169152

Humans as a potential reservoir for the emerging ST301 Shiga toxin-producing Escherichia coli clones of serotype O80:H2?. Frédéric Auvray, Federica Gigliucci, ..., Laurent Cavalié, ..., Éric Oswald, Clinical Microbiology and Infection 2025. DOI: 10.1016/j.cmi.2025.05.018

Rethinking the role of animals in antimicrobial resistance. Elissa Khamisse, Xavier Bertrand, ..., Éric Oswald, The Lancet Microbe 2025. DOI: 10.1016/j.lanmic.2025.101248

Differences in maternal diet fiber content influence patterns of gene expression and chromatin accessibility in fetuses and piglets. Smahane Chalabi, Linda M. P. Loonen, ..., Sarah Djebali, et al., Genomics 2025. DOI: 10.1016/j.ygeno.2025.110995

Kinetics of molecular patterns captured by mannose-binding lectin in septic shock correlate with clinical outcome: a monocentric prospective observational study. A. Bicart-See, Fanny Vardon Bounes, ..., Éric Oswald, Intensive Care Medicine Experimental 2025. DOI: 10.1186/s40635-025-00832-x

Human fallopian tube organoids provide a favourable environment for sperm motility. Nicolas Gatimel, Guillaume Perez, ..., David Sagnat, ..., Céline Deraison, Jean‐Paul Motta, ..., Nathalie Vergnolle, Human Reproduction 2025. DOI: 10.1093/humrep/deae258

Zoonotic potential of uropathogenic Escherichia coli lineages from companion animals. Nicolas Jousserand, Frédéric Auvray, Camille V. Chagneau, Laurent Cavalié, ..., Éric Oswald, Veterinary Research 2025. DOI: 10.1186/s13567-025-01493-0

Uncovering a new family of conserved virulence factors that promote the production of host‐damaging outer membrane vesicles in Gram‐negative bacteria. Audrey Goman, Bérengère Ize, ..., Camille V. Chagneau, Hélène Guet‐Revillet, Frédéric E. Taieb, ..., Laure David, ..., Priscilla Branchu, Éric Oswald, Journal of Extracellular Vesicles 2025. DOI: 10.1002/jev2.70032

Evolution of hepatobiliary involvement in cystic fibrosis children on CFTR modulators. Mélanie Auvray, Nolwenn Laborde, ..., Frédérick Barreau, ..., Emmanuel Mas, Journal of Cystic Fibrosis 2025. DOI: 10.1016/j.jcf.2025.05.003

Main genetic factors associated with inflammatory bowel diseases and their consequences on intestinal permeability: involvement in gut inflammation. Arthur Mauduit, Emmanuel Mas, ..., Sandrine Ménard, Frédérick Barreau, Journal of Gastroenterology 2025. DOI: 10.1007/s00535-025-02289-x

Bacterial nanoparticles as a potent and safe alternative to BCG for bladder cancer immunotherapy. Marine Colson, Arthur Aubry, ..., Éric Oswald, Laure David, Cancer Gene Therapy 2025. DOI: 10.1038/s41417-025-00984-8

Outer Membrane Vesicles as a Versatile Platform for Vaccine Development: Engineering Strategies, Applications and Challenges. Asja Garling, Frédéric Auvray, ..., Éric Oswald, Priscilla Branchu, Journal of Extracellular Vesicles 2025. DOI: 10.1002/jev2.70150

Modeling Postoperative Pathologic Ileus in Mice: A Simplified and Translational Approach. Romain Gauthier, Julie Thevenin, ..., Perrine Rousset, ..., Astrid Canivet, ..., Nathalie Vergnolle, Étienne Buscail, Céline Deraison, Neurogastroenterology & Motility 2025. DOI: 10.1111/nmo.70157

Bispecific nanobody® as a new pharmacological drug for the selective inhibition of Trypsin‐3. Mélissa David, Anaïs Faihy, ..., Anissa Edir, Astrid Canivet, ..., Nathalie Vergnolle, ..., Céline Deraison, British Journal of Pharmacology 2025. DOI: 10.1111/bph.70100

The hepatokine FGL1 regulates hepcidin and iron metabolism during anemia in mice by antagonizing BMP signaling. Ugo Sardo, Prunelle Perrier, ..., Jean Personnaz, Thanina Medjbeur, Aurore Desquesnes, Lisa Cannizzo, ..., Léon Kautz, Blood 2024. DOI: 10.1182/blood.2023022724

Human colonic organoids for understanding early events of familial adenomatous polyposis pathogenesis. Nolwenn Laborde, Alexandre Barusseaud, ..., Anne Laure Breton, Nathalie Vergnolle, ..., Frédérick Barreau, Claire Racaud‐Sultan, Emmanuel Mas, The Journal of Pathology 2024. DOI: 10.1002/path.6366

Chymotrypsin activity signals to intestinal epithelium by protease‐activated receptor‐dependent mechanisms. Simon Guignard, Mahmoud Saifeddine, ..., Laura Guiraud, David Sagnat, ..., Anissa Edir, ..., Étienne Buscail, ..., Nathalie Vergnolle, ..., Céline Deraison, Chrystelle Bonnart, British Journal of Pharmacology 2024. DOI: 10.1111/bph.16341

TRPV4 stimulates colonic afferents through mucosal release of ATP and glutamate. Michelle Y. Meng, Luke W Paine, David Sagnat, ..., Étienne Buscail, ..., Nathalie Vergnolle, et al., British Journal of Pharmacology 2024. DOI: 10.1111/bph.17408

Intestinal organoids to model Salmonella infection and its impact on progenitors. Yan Jin, Claire Racaud‐Sultan, ..., Anissa Edir, ..., Nathalie Vergnolle, Agnès Wiedemann, Scientific Reports 2024. DOI: 10.1038/s41598-024-65485-4

A draft human pangenome reference. Wen‐Wei Liao, Mobin Asri, ..., Jean Monlong, et al., Nature 2023. DOI: 10.1038/s41586-023-05896-x

S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis. Liwen Deng, Flavia G. Costa, ..., Céline Deraison, ..., Nathalie Vergnolle, et al., Cell 2023. DOI: 10.1016/j.cell.2023.10.019

Enhancer/gene relationships: Need for more reliable genome-wide reference sets. Tristan Hoellinger, Camille Mestre, ..., Sarah Djebali, Frontiers in Bioinformatics 2023. DOI: 10.3389/fbinf.2023.1092853

Perinatal foodborne titanium dioxide exposure-mediated dysbiosis predisposes mice to develop colitis through life. Caroline Carlé, Delphine Boucher, ..., Sandrine Ménard, ..., Emmanuel Mas, ..., Frédérick Barreau, Particle and Fibre Toxicology 2023. DOI: 10.1186/s12989-023-00555-5

Prevalence and characterization of the seven major serotypes of Shiga toxin-producing Escherichia coli (STEC) in veal calves slaughtered in France. Frédéric Auvray, Clémence Bièche-Terrier, ..., Éric Oswald, ..., Hubert Brugère, Veterinary Microbiology 2023. DOI: 10.1016/j.vetmic.2023.109754

PaintorPipe: a pipeline for genetic variant fine-mapping using functional annotations. Zoé Gerber, Michel Fisun, ..., Sarah Djebali, Bioinformatics Advances 2023. DOI: 10.1093/bioadv/vbad188

HlyF, an underestimated virulence factor of uropathogenic Escherichia coli. Camille V. Chagneau, Delphine Payros, ..., Carine Séguy, Clémence Massip, Priscilla Branchu, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, Clinical Microbiology and Infection 2023. DOI: 10.1016/j.cmi.2023.07.024

Intestinal involvement in lupus: From pathophysiology to therapeutic perspectives. Caroline Carlé, Emmanuel Mas, Frédérick Barreau, Lupus 2023. DOI: 10.1177/09612033231155840

Oxygen concentration modulates colibactin production. Nadège Bossuet‐Greif, Cécile Guyonnet, Camille V. Chagneau, ..., Marie Pénary, ..., Priscilla Branchu, Éric Oswald, Jean‐Philippe Nougayrède, Gut Microbes 2023. DOI: 10.1080/19490976.2023.2222437

TAGADA: a scalable pipeline to improve genome annotations with RNA-seq data. Cyril Kurylo, Cervin Guyomar, ..., Sarah Djebali, NAR Genomics and Bioinformatics 2023. DOI: 10.1093/nargab/lqad089

Scalable Nanopore sequencing of human genomes provides a comprehensive view of haplotype-resolved variation and methylation. Mikhail Kolmogorov, Kimberley J. Billingsley, ..., Jean Monlong, et al., Nature Methods 2023. DOI: 10.1038/s41592-023-01993-x

Pangenome graph construction from genome alignments with Minigraph-Cactus. Glenn Hickey, Jean Monlong, et al., Nature Biotechnology 2023. DOI: 10.1038/s41587-023-01793-w

Daphnanes diterpenes from the latex of Hura crepitans L. and their PKCζ-dependent anti-proliferative activity on colorectal cancer cells. Elise Crossay, Valérie Jullian, ..., David Sagnat, ..., Étienne Buscail, ..., Céline Deraison, Claire Racaud‐Sultan, et al., Bioorganic & Medicinal Chemistry 2023. DOI: 10.1016/j.bmc.2023.117366

Postoperative ileus after digestive surgery: Network meta‐analysis of pharmacological intervention. Étienne Buscail, Thibault Planchamp, ..., Jean‐Paul Motta, Nathalie Vergnolle, Céline Deraison, et al., British Journal of Clinical Pharmacology 2023. DOI: 10.1111/bcp.15878

Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptor. Jean Personnaz, Enzo B. Piccolo, et al., Science Advances 2022. DOI: 10.1126/sciadv.abg9055

Wild Boars as Reservoir of Highly Virulent Clone of Hybrid Shiga Toxigenic and Enterotoxigenic Escherichia coli Responsible for Edema Disease, France. Alexandre Perrat, Priscilla Branchu, ..., Hubert Brugère, Frédéric Auvray, Éric Oswald, Emerging Infectious Diseases 2022. DOI: 10.3201/eid2802.211491

Outer membrane vesicles produced by pathogenic strains of Escherichia coli block autophagic flux and exacerbate inflammasome activation. Laure David, Frédéric E. Taieb, Marie Pénary, ..., Éric Oswald, Autophagy 2022. DOI: 10.1080/15548627.2022.2054040

A novel toxic effect of foodborne trichothecenes: The exacerbation of genotoxicity. Marion Garofalo, Delphine Payros, Marie Pénary, Éric Oswald, Jean‐Philippe Nougayrède, et al., Environmental Pollution 2022. DOI: 10.1016/j.envpol.2022.120625

Respiratory syncytial virus ribonucleoproteins hijack microtubule Rab11 dependent transport for intracellular trafficking. Gina Cosentino, Katherine Marougka, Aurore Desquesnes, et al., PLOS Pathogens 2022. DOI: 10.1371/journal.ppat.1010619

Uncoupling the Hsp90 and DnaK chaperone activities revealed the in vivo relevance of their collaboration in bacteria. Marie Corteggiani, Nadège Bossuet‐Greif, Jean‐Philippe Nougayrède, ..., Éric Oswald, et al., Proceedings of the National Academy of Sciences 2022. DOI: 10.1073/pnas.2201779119

Prenatal stress induces changes in PAR2- and M3-dependent regulation of colon primitive cells. Mathieu Berger, Laura Guiraud, ..., David Sagnat, ..., Nathalie Vergnolle, Céline Deraison, ..., Claire Racaud‐Sultan, American Journal of Physiology-Gastrointestinal and Liver Physiology 2022. DOI: 10.1152/ajpgi.00061.2022

Postoperative ileus: A pharmacological perspective. Étienne Buscail, Céline Deraison, British Journal of Pharmacology 2022. DOI: 10.1111/bph.15800

Elafin and its precursor trappin‐2: What is their therapeutic potential for intestinal diseases?. Céline Deraison, Chrystelle Bonnart, ..., Nathalie Vergnolle, British Journal of Pharmacology 2022. DOI: 10.1111/bph.15985

Pangenomics enables genotyping of known structural variants in 5202 diverse genomes. Jouni Sirén, Jean Monlong, et al., Science 2021. DOI: 10.1126/science.abg8871

A condensate-hardening drug blocks RSV replication in vivo. Jennifer Risso-Ballester, Marie Galloux, ..., Aurore Desquesnes, et al., Nature 2021. DOI: 10.1038/s41586-021-03703-z

Colitis Linked to Endoplasmic Reticulum Stress Induces Trypsin Activity Affecting Epithelial Functions. Núria Solà Tapias, Alexandre Denadai‐Souza, ..., Anissa Edir, ..., Emmanuel Mas, ..., Céline Deraison, Chrystelle Bonnart, Nathalie Vergnolle, Frédérick Barreau, Journal of Crohn's and Colitis 2021. DOI: 10.1093/ecco-jcc/jjab035

A Toxic Friend: Genotoxic and Mutagenic Activity of the Probiotic Strain Escherichia coli Nissle 1917. Jean‐Philippe Nougayrède, Camille V. Chagneau, Jean‐Paul Motta, Nadège Bossuet‐Greif, ..., Frédéric E. Taieb, ..., Éric Oswald, mSphere 2021. DOI: 10.1128/msphere.00624-21

SHP2 drives inflammation-triggered insulin resistance by reshaping tissue macrophage populations. Romain Paccoud, Céline Saint-Laurent, ..., Jean Personnaz, et al., Science Translational Medicine 2021. DOI: 10.1126/scitranslmed.abe2587

Uropathogenic E. coli induces DNA damage in the bladder. Camille V. Chagneau, Clémence Massip, Nadège Bossuet‐Greif, ..., Jean‐Paul Motta, ..., Marie‐Paule Roth, Hélène Coppin, ..., Jean‐Philippe Nougayrède, Éric Oswald, PLOS Pathogens 2021. DOI: 10.1371/journal.ppat.1009310

Multiform antimicrobial resistance from a metabolic mutation. Sarah M. Schrader, Hélène Botella, ..., Julien Vaubourgeix, Science Advances 2021. DOI: 10.1126/sciadv.abh2037

Titanium dioxide particles from the diet: involvement in the genesis of inflammatory bowel diseases and colorectal cancer. Frédérick Barreau, Céline Tisseyre, Sandrine Ménard, et al., Particle and Fibre Toxicology 2021. DOI: 10.1186/s12989-021-00421-2

Revisiting definition and assessment of intestinal trans-epithelial passage. Hanna Ilchmann-Diounou, Marie Buléon, ..., Sandrine Ménard, Cellular and Molecular Life Sciences 2021. DOI: 10.1007/s00018-021-04000-8

Insights into evolution and coexistence of the colibactin- and yersiniabactin secondary metabolite determinants in enterobacterial populations. Haleluya Tesfaye Wami, Alexander Wallenstein, ..., Éric Oswald, et al., Microbial Genomics 2021. DOI: 10.1099/mgen.0.000577

Epithelial production of elastase is increased in inflammatory bowel disease and causes mucosal inflammation. Jean‐Paul Motta, Corinne Rolland, Anissa Edir, ..., David Sagnat, Chrystelle Bonnart, Perrine Rousset, Laura Guiraud, ..., Emmanuel Mas, ..., Étienne Buscail, ..., Nathalie Vergnolle, Céline Deraison, Mucosal Immunology 2021. DOI: 10.1038/s41385-021-00375-w

Next-Generation Cancer Biomarkers: Extracellular Vesicle DNA as a Circulating Surrogate of Tumor DNA. Samuel Amintas, V. Vendrely, ..., Étienne Buscail, Frontiers in Cell and Developmental Biology 2021. DOI: 10.3389/fcell.2020.622048

GSK3β, a Master Kinase in the Regulation of Adult Stem Cell Behavior. Claire Racaud‐Sultan, Nathalie Vergnolle, Cells 2021. DOI: 10.3390/cells10020225

Characterization of Human Colon Organoids From Inflammatory Bowel Disease Patients. Emilie d'Aldebert, Muriel Quaranta, ..., Claire Racaud‐Sultan, Emmanuel Mas, Céline Deraison, Nathalie Vergnolle, Frontiers in Cell and Developmental Biology 2020. DOI: 10.3389/fcell.2020.00363

The Genotoxin Colibactin Shapes Gut Microbiota in Mice. Sophie Tronnet, Pauline Floch, ..., Éric Oswald, mSphere 2020. DOI: 10.1128/msphere.00589-20

Expanded encyclopaedias of DNA elements in the human and mouse genomes. Federico Abascal, Reyes Acosta, ..., Sarah Djebali, et al., Nature 2020. DOI: 10.1038/s41586-020-2493-4

A fully human anti-BMP6 antibody reduces the need for erythropoietin in rodent models of the anemia of chronic disease. Verena Petzer, Piotr Tymoszuk, ..., Léon Kautz, et al., Blood 2020. DOI: 10.1182/blood.2019004653

Nonredundant functions of Mycobacterium tuberculosis chaperones promote survival under stress. Alexa P. Harnagel, Landys A. Lopez Quezada, ..., Julien Vaubourgeix, et al., Molecular Microbiology 2020. DOI: 10.1111/mmi.14615

Reduced Intestinal Inflammation With Lumacaftor/Ivacaftor in Adolescents With Cystic Fibrosis. Candice Tétard, Marie Mittaine, ..., Emmanuel Mas, et al., Journal of Pediatric Gastroenterology and Nutrition 2020. DOI: 10.1097/mpg.0000000000002864

The Interplay Between Genetic Risk Factors and Proteolytic Dysregulation in the Pathophysiology of Inflammatory Bowel Disease. Núria Solà-Tapias, Nathalie Vergnolle, ..., Frédérick Barreau, Journal of Crohn's and Colitis 2020. DOI: 10.1093/ecco-jcc/jjaa033

Biology of antimicrobial resistance and approaches to combat it. Sarah M. Schrader, Julien Vaubourgeix, et al., Science Translational Medicine 2020. DOI: 10.1126/scitranslmed.aaz6992

Genotyping structural variants in pangenome graphs using the vg toolkit. Glenn Hickey, David Heller, Jean Monlong, et al., Genome Biology 2020. DOI: 10.1186/s13059-020-1941-7

Increased Mucosal Thrombin is Associated with Crohn’s Disease and Causes Inflammatory Damage through Protease-activated Receptors Activation. Jean‐Paul Motta, Simone Palese, ..., Perrine Rousset, David Sagnat, Laura Guiraud, Anissa Edir, Carine Séguy, ..., Éric Oswald, ..., Céline Deraison, Nathalie Vergnolle, Journal of Crohn's and Colitis 2020. DOI: 10.1093/ecco-jcc/jjaa229

A variant erythroferrone disrupts iron homeostasis in SF3B1 -mutated myelodysplastic syndrome. Sabrina Bondu, Anne‐Sophie Alary, ..., Léon Kautz, et al., Science Translational Medicine 2019. DOI: 10.1126/scitranslmed.aav5467

Deciphering the interplay between the genotoxic and probiotic activities of Escherichia coli Nissle 1917. Clémence Massip, Priscilla Branchu, Nadège Bossuet‐Greif, Camille V. Chagneau, ..., Damien Dubois, Jean‐Philippe Nougayrède, Éric Oswald, PLOS Pathogens 2019. DOI: 10.1371/journal.ppat.1008029

Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2. Alberto Caminero, Justin L. McCarville, ..., Céline Deraison, ..., Nathalie Vergnolle, et al., Nature Communications 2019. DOI: 10.1038/s41467-019-09037-9

Intestinal Bile Acids Induce a Morphotype Switch in Vancomycin-Resistant Enterococcus that Facilitates Intestinal Colonization. Peter T. McKenney, Jinyuan Yan, Julien Vaubourgeix, et al., Cell Host & Microbe 2019. DOI: 10.1016/j.chom.2019.03.008

Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition. Elaine A. Ballinger, John Mosior, ..., Julien Vaubourgeix, et al., Science 2019. DOI: 10.1126/science.aau8959

Nod2 Protects the Gut From Experimental Colitis Spreading to Small Intestine. Ziad Al Nabhani, Dominique D. Berrebi, ..., Frédérick Barreau, et al., Journal of Crohn's and Colitis 2019. DOI: 10.1093/ecco-jcc/jjz196

Persistent Mycobacterium tuberculosis infection in mice requires PerM for successful cell division. Ruojun Wang, Kaj M. Kreutzfeldt, ..., Julien Vaubourgeix, et al., eLife 2019. DOI: 10.7554/elife.49570

Multi-species annotation of transcriptome and chromatin structure in domesticated animals. Sylvain Foissac, Sarah Djebali, et al., BMC Biology 2019. DOI: 10.1186/s12915-019-0726-5

Active thrombin produced by the intestinal epithelium controls mucosal biofilms. Jean‐Paul Motta, Alexandre Denadai‐Souza, David Sagnat, Laura Guiraud, Anissa Edir, Chrystelle Bonnart, ..., Perrine Rousset, ..., Carine Séguy, ..., Éric Oswald, ..., Céline Deraison, Nathalie Vergnolle, Nature Communications 2019. DOI: 10.1038/s41467-019-11140-w

Sexual dimorphism in PAR2-dependent regulation of primitive colonic cells. Julie Noguerol, Pierre-Jean Roustan, ..., Laura Guiraud, David Sagnat, Anissa Edir, Chrystelle Bonnart, ..., Céline Deraison, Nathalie Vergnolle, Claire Racaud‐Sultan, Biology of Sex Differences 2019. DOI: 10.1186/s13293-019-0262-6

The Colibactin Genotoxin Generates DNA Interstrand Cross-Links in Infected Cells. Nadège Bossuet‐Greif, Julien Vignard, Frédéric E. Taieb, ..., Damien Dubois, ..., Éric Oswald, Jean‐Philippe Nougayrède, mBio 2018. DOI: 10.1128/mbio.02393-17

Building Walls: Work That Never Ends. Hélène Botella, Julien Vaubourgeix, Trends in Microbiology 2018. DOI: 10.1016/j.tim.2018.11.006

Erythroferrone is not required for the glucoregulatory and hematologic effects of chronic erythropoietin treatment in mice. Richard Coffey, Ugo Sardo, Léon Kautz, et al., Physiological Reports 2018. DOI: 10.14814/phy2.13890

Targeting the Proteostasis Network for Mycobacterial Drug Discovery. Tania J. Lupoli, Julien Vaubourgeix, et al., ACS Infectious Diseases 2018. DOI: 10.1021/acsinfecdis.7b00231

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics. Alvaro Barbeira, Scott P. Dickinson, ..., Jean Monlong, et al., Nature Communications 2018. DOI: 10.1038/s41467-018-03621-1

Protectin D1 n-3 DPA and resolvin D5 n-3 DPA are effectors of intestinal protection. Thomas Gobbetti, Jesmond Dalli, ..., Nathalie Vergnolle, Céline Deraison, et al., Proceedings of the National Academy of Sciences 2017. DOI: 10.1073/pnas.1617290114

Immunoassay for human serum erythroferrone. Tomas Ganz, Grace Jung, ..., Léon Kautz, et al., Blood 2017. DOI: 10.1182/blood-2017-04-777987

The Food Contaminant Deoxynivalenol Exacerbates the Genotoxicity of Gut Microbiota. Delphine Payros, Ulrich Dobrindt, ..., Éric Oswald, et al., mBio 2017. DOI: 10.1128/mbio.00007-17

Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death. Laure Botella, Julien Vaubourgeix, et al., Nature Communications 2017. DOI: 10.1038/ncomms14731

An atlas of human long non-coding RNAs with accurate 5′ ends. Chung-Chau Hon, Jordan A. Ramilowski, ..., Sarah Djebali, et al., Nature 2017. DOI: 10.1038/nature21374

Epithelial expression and function of trypsin-3 in irritable bowel syndrome. Claire Rolland-Fourcade, Alexandre Denadai‐Souza, ..., Jean‐Paul Motta, ..., Céline Deraison, Nathalie Vergnolle, Gut 2017. DOI: 10.1136/gutjnl-2016-312094

Mycobacterium tuberculosis protease MarP activates a peptidoglycan hydrolase during acid stress. Hélène Botella, Julien Vaubourgeix, et al., The EMBO Journal 2017. DOI: 10.15252/embj.201695028

Distinct Spatiotemporal Dynamics of Peptidoglycan Synthesis between Mycobacterium smegmatis and Mycobacterium tuberculosis. Hélène Botella, Guangli Yang, ..., Julien Vaubourgeix, mBio 2017. DOI: 10.1128/mbio.01183-17

Erythroferrone and matriptase‐2 independently regulate hepcidin expression. Sharraya Aschemeyer, Victoria R. Gabayan, ..., Léon Kautz, American Journal of Hematology 2017. DOI: 10.1002/ajh.24672

Retrograde Trafficking Inhibitor of Shiga Toxins Reduces Morbidity and Mortality of Mice Infected with Enterohemorrhagic Escherichia coli. Thomas Sécher, Ayaka Shima, ..., Éric Oswald, Antimicrobial Agents and Chemotherapy 2015. DOI: 10.1128/aac.00455-15

Stressed Mycobacteria Use the Chaperone ClpB to Sequester Irreversibly Oxidized Proteins Asymmetrically Within and Between Cells. Julien Vaubourgeix, Gang Lin, et al., Cell Host & Microbe 2015. DOI: 10.1016/j.chom.2014.12.008

Disruption of an M. tuberculosis Membrane Protein Causes a Magnesium-dependent Cell Division Defect and Failure to Persist in Mice. Nichole Goodsmith, Xinzheng Victor Guo, ..., Julien Vaubourgeix, et al., PLOS Pathogens 2015. DOI: 10.1371/journal.ppat.1004645

Apelin targets gut contraction to control glucose metabolism via the brain. Audren Fournel, Anne Drougard, ..., Perrine Rousset, ..., Nathalie Vergnolle, et al., Gut 2015. DOI: 10.1136/gutjnl-2015-310230

The Genotoxin Colibactin Exacerbates Lymphopenia and Decreases Survival Rate in Mice Infected With Septicemic Escherichia coli. Ingrid Marcq, P. Martin, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, Journal of Infectious Diseases 2014. DOI: 10.1093/infdis/jiu071

N,C-Capped Dipeptides with Selectivity for Mycobacterial Proteasome over Human Proteasomes: Role of S3 and S1 Binding Pockets. Gang Lin, Tamutenda Chidawanyika, ..., Julien Vaubourgeix, et al., Journal of the American Chemical Society 2013. DOI: 10.1021/ja400021x

Interplay between Siderophores and Colibactin Genotoxin Biosynthetic Pathways in Escherichia coli. Patricia Martín, Ingrid Marcq, ..., Marie Pénary, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, PLoS Pathogens 2013. DOI: 10.1371/journal.ppat.1003437

A Common Mechanism of Inhibition of the Mycobacterium tuberculosis Mycolic Acid Biosynthetic Pathway by Isoxyl and Thiacetazone. Anna E. Grzegorzewicz, Jana Korduláková, ..., Julien Vaubourgeix, et al., Journal of Biological Chemistry 2012. DOI: 10.1074/jbc.m112.400994

Deciphering sulfoglycolipids of Mycobacterium tuberculosis. Emilie Layre, Diane Cala‐De Paepe, ..., Julien Vaubourgeix, et al., Journal of Lipid Research 2011. DOI: 10.1194/jlr.m013482

Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells. Gabriel Cuevas Ramos, Claude R. Petit, ..., Éric Oswald, Jean‐Philippe Nougayrède, Proceedings of the National Academy of Sciences 2010. DOI: 10.1073/pnas.1001261107

Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ. Jichan Jang, Alexandre Stella, ..., Julien Vaubourgeix, et al., Microbiology 2010. DOI: 10.1099/mic.0.038133-0

Pathogenic Bacteria Target NEDD8-Conjugated Cullins to Hijack Host-Cell Signaling Pathways. Grégory Jubelin, Frédéric E. Taieb, ..., Marie Pénary, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, PLoS Pathogens 2010. DOI: 10.1371/journal.ppat.1001128

S-Adenosyl-N-decyl-aminoethyl, a Potent Bisubstrate Inhibitor of Mycobacterium tuberculosis Mycolic Acid Methyltransferases. Julien Vaubourgeix, F. Bardou, et al., Journal of Biological Chemistry 2009. DOI: 10.1074/jbc.m809599200

Foamy Macrophages from Tuberculous Patients’ Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence. Pascale Peyron, Julien Vaubourgeix, et al., PLoS Pathogens 2008. DOI: 10.1371/journal.ppat.1000204

Escherichia coli Induces DNA Double-Strand Breaks in Eukaryotic Cells. Jean‐Philippe Nougayrède, Stefan Homburg, Frédéric E. Taieb, ..., Éric Oswald, Science 2006. DOI: 10.1126/science.1127059

Role of Tir and Intimin in the Virulence of Rabbit EnteropathogenicEscherichia coliSerotype O103:H2. Olivier Marchès, Jean‐Philippe Nougayrède, ..., Éric Oswald, Infection and Immunity 2000. DOI: 10.1128/iai.68.4.2171-2182.2000

A new cytolethal distending toxin (CDT) from Escherichia coli producing CNF2 blocks HeLa cell division in G2/M phase. Sylvie Y. Pérès, Olivier Marchès, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, Molecular Microbiology 1997. DOI: 10.1046/j.1365-2958.1997.4181785.x