Ablation of Hepatocyte Derived‐FGL1 Does Not Aggravate Metabolic Dysfunction‐Associated Steatotic Liver Disease. Jean Personnaz, Lisa Cannizzo, ..., Aurore Desquesnes, ..., Léon Kautz, The FASEB Journal 2025. DOI: 10.1096/fj.202501997r

Preadipocyte IL-13/IL-13Rα1 signaling regulates beige adipogenesis through modulation of PPARγ activity. Alexandra R Yesian, Mayer M. Chalom, ..., Jean Personnaz, et al., Journal of Clinical Investigation 2025. DOI: 10.1172/jci169152

AKT-mediated phosphorylation of TSC2 controls stimulus- and tissue-specific mTORC1 signaling and organ growth. Yann Cormerais, S. Lapp, ..., Jean Personnaz, et al., Developmental Cell 2025. DOI: 10.1016/j.devcel.2025.05.008

Fibrinogen‐like 1: A hepatokine linking liver physiology to hematology. Jean Personnaz, Hervé Guillou, Léon Kautz, HemaSphere 2024. DOI: 10.1002/hem3.115

FGL1, une nouvelle cible pour le traitement de l’anémie ?. Thanina Medjbeur, Jean Personnaz, Léon Kautz, médecine/sciences 2024. DOI: 10.1051/medsci/2024123

The hepatokine FGL1 regulates hepcidin and iron metabolism during anemia in mice by antagonizing BMP signaling. Ugo Sardo, Prunelle Perrier, ..., Jean Personnaz, Thanina Medjbeur, Aurore Desquesnes, Lisa Cannizzo, ..., Julie Thevenin, ..., Léon Kautz, Blood 2024. DOI: 10.1182/blood.2023022724

Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptor. Jean Personnaz, Enzo Piccolo, et al., Science Advances 2022. DOI: 10.1126/sciadv.abg9055

SHP2 drives inflammation-triggered insulin resistance by reshaping tissue macrophage populations. Romain Paccoud, Céline Saint-Laurent, ..., Jean Personnaz, et al., Science Translational Medicine 2021. DOI: 10.1126/scitranslmed.abe2587