AKT-mediated phosphorylation of TSC2 controls stimulus- and tissue-specific mTORC1 signaling and organ growth. Yann Cormerais, Samuel C. Lapp, ..., Jean Personnaz, et al., Developmental Cell 2025. DOI: 10.1016/j.devcel.2025.05.008

Preadipocyte IL-13/IL-13Rα1 signaling regulates beige adipogenesis through modulation of PPARγ activity. Alexandra R Yesian, Mayer M. Chalom, ..., Jean Personnaz, et al., Journal of Clinical Investigation 2025. DOI: 10.1172/jci169152

The hepatokine FGL1 regulates hepcidin and iron metabolism during anemia in mice by antagonizing BMP signaling. Ugo Sardo, Prunelle Perrier, ..., Jean Personnaz, Thanina Medjbeur, Aurore Desquesnes, Lisa Cannizzo, ..., Léon Kautz, Blood 2024. DOI: 10.1182/blood.2023022724

Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptor. Jean Personnaz, Enzo B. Piccolo, et al., Science Advances 2022. DOI: 10.1126/sciadv.abg9055

SHP2 drives inflammation-triggered insulin resistance by reshaping tissue macrophage populations. Romain Paccoud, Céline Saint-Laurent, ..., Jean Personnaz, et al., Science Translational Medicine 2021. DOI: 10.1126/scitranslmed.abe2587