Rigosertib promotes expression of the antimicrobial peptide beta-defensin-3 in human cells. Weronika Wozniak, David Sagnat, ..., Étienne Buscail, ..., Nathalie Vergnolle, et al., Scientific Reports 2026. DOI: 10.1038/s41598-026-79053-5

Low prevalence of celiac disease in French children, a nationwide study. Marwa Hmimou, Chloé Girard, ..., Emmanuel Mas, Pediatric Research 2026. DOI: 10.1038/s41390-026-05545-9

Perinatal exposure to nano-polystyrene: deleterious imprinting on inflammatory bowel diseases. Melvin Airaud, Amandine Roldan, ..., Lisa Isoard, ..., Sandrine Ménard, Frédérick Barreau, Particle and Fibre Toxicology 2026. DOI: 10.1186/s12989-026-00700-w

Moraxella species isolated from blood cultures in Europe (MORAXEu): a multicentre study of epidemiology and antimicrobial susceptibility with complementary phylogenomic analysis of publicly available genomes. Tone Tønjum, Vinicius da Silva Franklin-Duarte, ..., Damien Dubois, Pauline Floch, et al., European Journal of Clinical Microbiology & Infectious Diseases 2026. DOI: 10.1007/s10096-026-05640-z

A Multiagent Quantitative Microbial Risk Assessment of Raw Milk Cheeses: From Farm-Level Practices to Consumer Risk. Laurent Guillier, Estelle Chaix, Frédéric Auvray, ..., Éric Oswald, et al., Journal of Food Protection 2026. DOI: 10.1016/j.jfp.2026.100913

Intestinal epithelium impairment in cystic fibrosis: What consequences in clinical practice?. Caroline Carlé, Marie Mittaine, ..., Nolwenn Laborde, Frédérick Barreau, Emmanuel Mas, World Journal of Gastroenterology 2026. DOI: 10.3748/wjg.121071

Fast-growing intracellular Mycobacterium tuberculosis populations evade antibiotic treatment. Nathan J. Day, Baptiste Pradel, ..., Julien Vaubourgeix, et al., Nature Communications 2026. DOI: 10.1038/s41467-026-75915-8

Exclusive enteral nutrition containing transforming growth factor‐β improves intestinal barrier function in a colitis mouse model. Kawthar Boumessid, Vickie Lacroix, ..., Frédérick Barreau, Emmanuel Mas, Journal of Pediatric Gastroenterology and Nutrition 2026. DOI: 10.1002/jpn3.70517

Intestinal toxicity of functionalized polystyrene nanoplastics in NOD2 models of Crohn’s disease susceptibility. Manon Dussol, Sandrine Ménard, ..., Frédérick Barreau, et al., Frontiers in Toxicology 2026. DOI: 10.3389/ftox.2026.1839932

Accelerated Epigenetic and Inflammatory Aging and Intrinsic Capacity. Laure Rouch, Philipe de Souto Barreto, ..., Nathalie Vergnolle, Jean‐Paul Motta, ..., Pauline Floch, Céline Deraison, Chrystelle Bonnart, et al., JAMA Network Open 2026. DOI: 10.1001/jamanetworkopen.2026.24102

NLRP3 inflammasome partially mediates genotoxic E. coli infection in lean but not in genetically obese mice. Pauline Floch, Cécile Goursat, ..., Éric Oswald, Priscilla Branchu, et al., iScience 2026. DOI: 10.1016/j.isci.2026.116674

L26/O-068 Tubal extracellular vesicles from human fallopian tubes and derived organoids promote the maintenance of sperm fertilising capacity. E. Bruno, David Sagnat, ..., Nathalie Vergnolle, et al., Human Reproduction 2026. DOI: 10.1093/humrep/deag083.068

High thrombin activity associated with crohn’s disease induces microbiota pathogenicity contributing to mucosal inflammation. Guillaume Le Cosquer, Melissa Pannier, ..., Laura Guiraud, ..., Perrine Rousset, ..., Étienne Buscail, ..., Céline Deraison, Nathalie Vergnolle, Jean‐Paul Motta, Gut Microbes 2026. DOI: 10.1080/19490976.2026.2687903

Mtb-Timer: a fluorescent reporter to visualize Mycobacterium tuberculosis replication and antibiotic responses. Víctor Campo-Pérez, Chak Hon Luk, ..., Julien Vaubourgeix, et al., mSystems 2026. DOI: 10.1128/msystems.01796-25

The role of dietary patterns on epigenetic and inflammatory aging based on the INSPIRE-T study. Natasha Aparecida Grande de França, Yves Rolland, ..., Nathalie Vergnolle, Jean‐Paul Motta, ..., Pauline Floch, Céline Deraison, Chrystelle Bonnart, et al., Communications Medicine 2026. DOI: 10.1038/s43856-026-01643-1

Rise of Neisseria gonorrhoeae with mosaic penA-34, France, 2018–2023. François Caméléna, Manel Mérimèche, ..., Damien Dubois, ..., Marion Grare, et al., Antimicrobial Agents and Chemotherapy 2026. DOI: 10.1128/aac.01919-25

Bidirectional associations between biological aging, cardiovascular health, and cardiovascular risk: findings from the INSPIRE-T lifespan cohort. Mathilde Strumia, Vanina Bongard, ..., Nathalie Vergnolle, Jean‐Paul Motta, ..., Pauline Floch, Céline Deraison, Chrystelle Bonnart, et al., GeroScience 2026. DOI: 10.1007/s11357-026-02251-6

Epidemiology and antimicrobial resistance patterns of Aeromonas species in Europe, 2020-2024 (AEuROMONAS). Matteo Boattini, Paulo André Dias Bastos, ..., Damien Dubois, Pauline Floch, et al., Diagnostic Microbiology and Infectious Disease 2026. DOI: 10.1016/j.diagmicrobio.2026.117384

Minor non-fermenting Gram-negative bacilli in Europe, 2020–2024 (MINOFEu). Gabriele Bianco, Paulo André Dias Bastos, ..., Damien Dubois, Clémence Massip, et al., International Journal of Antimicrobial Agents 2026. DOI: 10.1016/j.ijantimicag.2026.107772

Hepatitis vírica. Camille Bréhin, Clothilde Marbach, Nolwenn Laborde, et al., EMC - Pediatría 2026. DOI: 10.1016/s1245-1789(25)51334-3

Is Klebsiella pneumoniae -associated bovine mastitis an emerging public health issue? A One Health perspective. Delphine Payros, Frédéric Auvray, ..., Éric Oswald, ASM Animal Microbiology 2026. DOI: 10.1128/asmam.00023-25

Long‐Term Effects of Xenotransplantation of Human Enteric Glia in an Immunocompetent Rat Model of Acute Brain Injury. Nina Colitti, Edwige Rice, ..., Étienne Buscail, ..., Nathalie Vergnolle, et al., Advanced Science 2026. DOI: 10.1002/advs.202503362

Cyclic exclusive enteral nutrition versus partial enteral nutrition to maintain long-term drug-free remission in paediatric Crohn’s disease (CD-HOPE): an open-label, endpoint-blinded, randomised controlled trial. Bénédicte Pigneur, Christine Martinez‐Vinson, ..., Anne Laure Breton, et al., The Lancet Gastroenterology & Hepatology 2026. DOI: 10.1016/s2468-1253(25)00262-6

Nontuberculous Mycobacterial Lymphadenitis in Children: A French Retrospective Multicenter Study on Epidemiology, Management Strategy and Outcome Over the Last Decade. Cécile Le Brun, Hélène Guet‐Revillet, ..., Camille Bréhin, et al., Pediatric Infectious Disease Journal 2026. DOI: 10.1097/inf.0000000000005144

Comment un mécanisme de résistance aux antibiotiques favorise la virulence bactérienne. Audrey Goman, Lola Manenc, ..., Priscilla Branchu, Éric Oswald, médecine/sciences 2026. DOI: 10.1051/medsci/2025252

A contemporary overview of severe community-acquired bacterial infections in pediatric intensive care units. Michaël Levy, Anne-Lise Mary, ..., Camille Bréhin, ..., Damien Dubois, ..., Camille Bréhin, ..., Damien Dubois, et al., Annals of Intensive Care 2026. DOI: 10.1016/j.aicoj.2026.100112

Evaluation of the prebiotic potential of polyphenol-rich plant extracts in a mouse model of colitis. Damien Guillemet, Perrine Rousset, ..., Anissa Edir, ..., Laura Guiraud, Nathalie Vergnolle, Jean‐Paul Motta, Microbiota and Host 2025. DOI: 10.1530/mah-25-0007

Clinical and microbiological characterization of intraoperative findings suggestive of endocarditis: a retrospective cohort study. Jean-Roch Le Henaff, Lydie Porte, Clémence Massip, ..., Clémence Massip, et al., Clinical Microbiology and Infection 2025. DOI: 10.1016/j.cmi.2025.12.006

Kinetics of molecular patterns captured by mannose-binding lectin in septic shock correlate with clinical outcome: a monocentric prospective observational study. A. Bicart-See, Fanny Vardon Bounes, ..., Éric Oswald, Intensive Care Medicine Experimental 2025. DOI: 10.1186/s40635-025-00832-x

Oral indomethacin modifies small intestine biofilms and host-microbe interaction mediators. Arezoo Haghighi, András S. Tóth, ..., Jean‐Paul Motta, Nathalie Vergnolle, et al., Life Sciences 2025. DOI: 10.1016/j.lfs.2025.124114

Real-life assessment of the VirClia® IgG chemiluminescence test for the diagnosis of Bartonella henselae infection. Candice Pollani, Pauline Floch, ..., Damien Dubois, Clémence Massip, Diagnostic Microbiology and Infectious Disease 2025. DOI: 10.1016/j.diagmicrobio.2025.117187

A Non-genotoxic Variant of Escherichia coli Nissle 1917 EcN 2.0 Overexpressing Microcins Reduces Intestinal Carriage of ST131 ESBL-Producing Escherichia coli. Nicolas Jousserand, Benjamin Massiera, ..., Éric Oswald, et al., Probiotics and Antimicrobial Proteins 2025. DOI: 10.1007/s12602-025-10777-y

Bacterial nanoparticles as a potent and safe alternative to BCG for bladder cancer immunotherapy. Marine Colson, Arthur Aubry, ..., Éric Oswald, Laure David, Cancer Gene Therapy 2025. DOI: 10.1038/s41417-025-00984-8

Intravenous Antibiotic Treatment With Oral Relay in Pediatric Intracranial Abscesses: A 20-Year Descriptive Monocentric Cohort in France. Audrey Lassalle, Éloïse Baudou, ..., Damien Dubois, ..., Camille Bréhin, et al., Pediatric Infectious Disease Journal 2025. DOI: 10.1097/inf.0000000000005018

Rethinking the role of animals in antimicrobial resistance. Elissa Khamisse, Xavier Bertrand, ..., Éric Oswald, The Lancet Microbe 2025. DOI: 10.1016/j.lanmic.2025.101248

Modeling Postoperative Pathologic Ileus in Mice: A Simplified and Translational Approach. Romain Gauthier, Julie Thevenin, ..., Perrine Rousset, ..., Astrid Canivet, ..., Nathalie Vergnolle, Étienne Buscail, Céline Deraison, Neurogastroenterology & Motility 2025. DOI: 10.1111/nmo.70157

Outer Membrane Vesicles as a Versatile Platform for Vaccine Development: Engineering Strategies, Applications and Challenges. Asja Garling, Frédéric Auvray, ..., Éric Oswald, Priscilla Branchu, Journal of Extracellular Vesicles 2025. DOI: 10.1002/jev2.70150

Severe Group A Streptococcus Infection among Children, France, 2022–2024. Montserrat Sierra Colomina, Alix Flamant, ..., Damien Dubois, ..., Camille Bréhin, Emerging Infectious Diseases 2025. DOI: 10.3201/eid3109.250245

Main genetic factors associated with inflammatory bowel diseases and their consequences on intestinal permeability: involvement in gut inflammation. Arthur Mauduit, Emmanuel Mas, ..., Sandrine Ménard, Frédérick Barreau, Journal of Gastroenterology 2025. DOI: 10.1007/s00535-025-02289-x

Ablation of Hepatocyte Derived‐ FGL1 Does Not Aggravate Metabolic Dysfunction‐Associated Steatotic Liver Disease. Jean Personnaz, Lisa Cannizzo, ..., Aurore Desquesnes, ..., Léon Kautz, The FASEB Journal 2025. DOI: 10.1096/fj.202501997r

Studying Pseudomonas aeruginosa pathogenesis: the need for more than just the PAO1 strain. Laure David, Audrey Goman, ..., Frédéric E. Taieb, Priscilla Branchu, Éric Oswald, Microbiology Spectrum 2025. DOI: 10.1128/spectrum.00665-25

Opinion of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES) on defining pathogenic strains of Shiga toxin‐producing Escherichia coli. Philippe Fravalo, Frédéric Auvray, ..., Éric Oswald, et al., Food Risk Assess Europe 2025. DOI: 10.2903/fr.efsa.2025.fr-0065

Optimization and stability evaluation of a pediatric spironolactone oral suspension: Formulation development and analytical validation. Roxanne Desquines, Zoubeir Ramjaun, ..., Laurent Cavalié, Camille V. Chagneau, et al., European Journal of Pharmaceutics and Biopharmaceutics 2025. DOI: 10.1016/j.ejpb.2025.114801

A European survey on anaerobes from paediatric blood cultures: a comparative analysis with adults. Matteo Boattini, Arianna Aceti, ..., Pauline Floch, Clémence Massip, et al., European Journal of Clinical Microbiology & Infectious Diseases 2025. DOI: 10.1007/s10096-025-05185-7

Bispecific nanobody® as a new pharmacological drug for the selective inhibition of Trypsin‐3. Mélissa David, Anaïs Faihy, ..., Anissa Edir, Astrid Canivet, ..., Nathalie Vergnolle, ..., Céline Deraison, British Journal of Pharmacology 2025. DOI: 10.1111/bph.70100

AKT-mediated phosphorylation of TSC2 controls stimulus- and tissue-specific mTORC1 signaling and organ growth. Yann Cormerais, Samuel C. Lapp, ..., Jean Personnaz, et al., Developmental Cell 2025. DOI: 10.1016/j.devcel.2025.05.008

Evolution of hepatobiliary involvement in cystic fibrosis children on CFTR modulators. Mélanie Auvray, Nolwenn Laborde, ..., Frédérick Barreau, ..., Emmanuel Mas, Journal of Cystic Fibrosis 2025. DOI: 10.1016/j.jcf.2025.05.003

Humans as a potential reservoir for the emerging ST301 Shiga toxin-producing Escherichia coli clones of serotype O80:H2?. Frédéric Auvray, Federica Gigliucci, ..., Laurent Cavalié, ..., Éric Oswald, Clinical Microbiology and Infection 2025. DOI: 10.1016/j.cmi.2025.05.018

Pathogenicity of commensal gut biofilm in prefrail aging. Guillaume Le Cosquer, Melissa Pannier, ..., Céline Deraison, Nathalie Vergnolle, Jean‐Paul Motta, et al., npj Biofilms and Microbiomes 2025. DOI: 10.1038/s41522-025-00716-8

Polygenic risk score prediction accuracy convergence. Léo Henches, Jihye Kim, ..., Arthur Frouin, ..., Sarah Djebali, et al., Human Genetics and Genomics Advances 2025. DOI: 10.1016/j.xhgg.2025.100457

The associations between biological markers of aging and appetite loss across adulthood: retrospective case–control data from the INSPIRE-T study. Annelie Turesson, Afsaneh Koochek, ..., Nathalie Vergnolle, Jean‐Paul Motta, ..., Céline Deraison, et al., GeroScience 2025. DOI: 10.1007/s11357-025-01691-w

Preadipocyte IL-13/IL-13Rα1 signaling regulates beige adipogenesis through modulation of PPARγ activity. Alexandra R Yesian, Mayer M. Chalom, ..., Jean Personnaz, et al., Journal of Clinical Investigation 2025. DOI: 10.1172/jci169152

Opinion of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES) on the risks associated with the consumption of nitrites and nitrates. Marie‐Louise Scippo, Pierre‐Marie Badot, ..., Frédéric Auvray, ..., Éric Oswald, et al., Food Risk Assess Europe 2025. DOI: 10.2903/fr.efsa.2025.fr-0059

Opinion and report of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES) on the assessment of the impact of fox population dynamics on public health. Emmanuelle Gilot‐Fromont, Isabelle Villena, ..., Frédéric Auvray, ..., Éric Oswald, et al., Food Risk Assess Europe 2025. DOI: 10.2903/fr.efsa.2025.fr-0062

Opinion of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES) on the presence of Toxocara spp. parasites in wild boar meat. Philippe Fravalo, Frédéric Auvray, ..., Éric Oswald, et al., Food Risk Assess Europe 2025. DOI: 10.2903/fr.efsa.2025.fr-0058

Zoonotic potential of uropathogenic Escherichia coli lineages from companion animals. Nicolas Jousserand, Frédéric Auvray, Camille V. Chagneau, Laurent Cavalié, ..., Éric Oswald, Veterinary Research 2025. DOI: 10.1186/s13567-025-01493-0

In vitro activity of ceftolozane/tazobactam, ceftazidime/avibactam and cefiderocol against clinical isolates of non-aeruginosa Pseudomonas. Lucie Thene, Pauline Floch, Camille V. Chagneau, Damien Dubois, Clémence Massip, Journal of Antimicrobial Chemotherapy 2025. DOI: 10.1093/jac/dkaf067

Comparative analysis of dietary iron deprivation and supplementation in a murine model of colitis. Thanina Medjbeur, Ugo Sardo, ..., Léon Kautz, FASEB BioAdvances 2025. DOI: 10.1096/fba.2025-00022

Diagnostic and epidemiological landscape of anaerobic bacteria in Europe, 2020–2023 (ANAEuROBE). Matteo Boattini, Gabriele Bianco, ..., Pauline Floch, Clémence Massip, et al., International Journal of Antimicrobial Agents 2025. DOI: 10.1016/j.ijantimicag.2025.107478

Development of intimin-enriched outer membrane vesicles (OMVs) as a vaccine to control intestinal carriage of Enterohemorrhagic Escherichia coli. Asja Garling, Cécile Goursat, Carine Séguy, ..., Jean‐Philippe Nougayrède, Éric Oswald, Frédéric Auvray, Priscilla Branchu, Vaccine 2025. DOI: 10.1016/j.vaccine.2025.126899

Advancing long-read nanopore genome assembly and accurate variant calling for rare disease detection. Shloka Negi, Sarah L. Stenton, ..., Jean Monlong, et al., The American Journal of Human Genetics 2025. DOI: 10.1016/j.ajhg.2025.01.002

Differences in maternal diet fiber content influence patterns of gene expression and chromatin accessibility in fetuses and piglets. Smahane Chalabi, Linda M. P. Loonen, ..., Sarah Djebali, et al., Genomics 2025. DOI: 10.1016/j.ygeno.2025.110995

Deciphering the interplay between biology and physics with a finite element method-implemented vertex organoid model: A tool for the mechanical analysis of cell behavior on a spherical organoid shell. Julien Laussu, Déborah Michel, ..., Frédérick Barreau, Emmanuel Mas, et al., PLOS Computational Biology 2025. DOI: 10.1371/journal.pcbi.1012681

Human fallopian tube organoids provide a favourable environment for sperm motility. Nicolas Gatimel, Guillaume Perez, ..., David Sagnat, ..., Céline Deraison, Jean‐Paul Motta, ..., Nathalie Vergnolle, Human Reproduction 2025. DOI: 10.1093/humrep/deae258

Uncovering a new family of conserved virulence factors that promote the production of host‐damaging outer membrane vesicles in Gram‐negative bacteria. Audrey Goman, Bérengère Ize, ..., Camille V. Chagneau, Hélène Guet‐Revillet, Frédéric E. Taieb, ..., Laure David, ..., Priscilla Branchu, Éric Oswald, Journal of Extracellular Vesicles 2025. DOI: 10.1002/jev2.70032

Human colonic organoids for understanding early events of familial adenomatous polyposis pathogenesis. Nolwenn Laborde, Alexandre Barusseaud, ..., Anne Laure Breton, Nathalie Vergnolle, ..., Frédérick Barreau, Claire Racaud‐Sultan, Emmanuel Mas, The Journal of Pathology 2024. DOI: 10.1002/path.6366

TRPV4 stimulates colonic afferents through mucosal release of ATP and glutamate. Michelle Y. Meng, Luke W Paine, David Sagnat, ..., Étienne Buscail, ..., Nathalie Vergnolle, et al., British Journal of Pharmacology 2024. DOI: 10.1111/bph.17408

FGL1, une nouvelle cible pour le traitement de l’anémie ?. Thanina Medjbeur, Jean Personnaz, Léon Kautz, médecine/sciences 2024. DOI: 10.1051/medsci/2024123

Proteolytic bacteria expansion during colitis amplifies inflammation through cleavage of the external domain of PAR2. Liam Emile Rondeau, B Barbosa da Luz, ..., Céline Deraison, ..., Nathalie Vergnolle, et al., Gut Microbes 2024. DOI: 10.1080/19490976.2024.2387857

Evaluation of several routine methods for fosfomycin and mecillinam susceptibility testing of Enterobacterales urine isolates. Clémence Massip, Lucie Feletti, Camille V. Chagneau, ..., Damien Dubois, Journal of Antimicrobial Chemotherapy 2024. DOI: 10.1093/jac/dkae271

Intestinal organoids to model Salmonella infection and its impact on progenitors. Yan Jin, Claire Racaud‐Sultan, ..., Anissa Edir, ..., Nathalie Vergnolle, Agnès Wiedemann, Scientific Reports 2024. DOI: 10.1038/s41598-024-65485-4

Mapping the scientific output of organoids for animal and human modeling infectious diseases: a bibliometric assessment. Yan Jin, Jean Monlong, ..., Agnès Wiedemann, Veterinary Research 2024. DOI: 10.1186/s13567-024-01333-7

Compliance with antibiotic therapy guidelines in french paediatric intensive care units: a multicentre observational study. Romain Amadieu, Camille Bréhin, ..., Damien Dubois, et al., BMC Infectious Diseases 2024. DOI: 10.1186/s12879-024-09472-0

Predictive Capacity of the Integrated Care for Older People Screening Tool for Intrinsic Capacity Impairments: Results From the INSPIRE-T Cohort. Kelly Virecoulon Giudici, Philipe de Souto Barreto, ..., Jean‐Paul Motta, ..., Pauline Floch, et al., The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences 2024. DOI: 10.1093/gerona/glae112

Chymotrypsin activity signals to intestinal epithelium by protease‐activated receptor‐dependent mechanisms. Simon Guignard, Mahmoud Saifeddine, ..., Laura Guiraud, David Sagnat, ..., Anissa Edir, ..., Étienne Buscail, ..., Nathalie Vergnolle, ..., Céline Deraison, Chrystelle Bonnart, British Journal of Pharmacology 2024. DOI: 10.1111/bph.16341

Necrotizing pneumonia in children: Report of 25 cases between 2008 and 2018 at a French tertiary care center. Manon Cathalau, Marine Michelet, ..., Damien Dubois, ..., Camille Bréhin, Archives de Pédiatrie 2024. DOI: 10.1016/j.arcped.2023.12.004

Enterobacterales carrying chromosomal AmpC β-lactamases in Europe (EuESCPM): Epidemiology and antimicrobial resistance burden from a cohort of 27 hospitals, 2020–2022. Matteo Boattini, Gabriele Bianco, ..., Pauline Floch, Clémence Massip, et al., International Journal of Antimicrobial Agents 2024. DOI: 10.1016/j.ijantimicag.2024.107115

A human anti-matriptase-2 antibody limits iron overload, α-globin aggregates, and splenomegaly in β-thalassemic mice. Matthew Wake, Anaïs Palin, Audrey Belot, ..., Céline Besson‐Fournier, Chloé Latour, ..., Hélène Coppin, Marie‐Paule Roth, ..., Delphine Meynard, Blood Advances 2024. DOI: 10.1182/bloodadvances.2023012010

The hepatokine FGL1 regulates hepcidin and iron metabolism during anemia in mice by antagonizing BMP signaling. Ugo Sardo, Prunelle Perrier, ..., Jean Personnaz, Thanina Medjbeur, Aurore Desquesnes, Lisa Cannizzo, ..., Léon Kautz, Blood 2024. DOI: 10.1182/blood.2023022724

PaintorPipe: a pipeline for genetic variant fine-mapping using functional annotations. Zoé Gerber, Michel Fisun, ..., Sarah Djebali, Bioinformatics Advances 2023. DOI: 10.1093/bioadv/vbad188

Involvement of CATSPER 2 mutation in a familial context of unexplained infertility and fertilization failure associated with hearing loss: a case report. Simon Guignard, Christina Guillaume, ..., Nathalie Vergnolle, Céline Deraison, Chrystelle Bonnart, et al., F&S Reports 2023. DOI: 10.1016/j.xfre.2023.12.003

Perinatal foodborne titanium dioxide exposure-mediated dysbiosis predisposes mice to develop colitis through life. Caroline Carlé, Delphine Boucher, ..., Sandrine Ménard, ..., Emmanuel Mas, ..., Frédérick Barreau, Particle and Fibre Toxicology 2023. DOI: 10.1186/s12989-023-00555-5

Transition care to adolescent hepatology in a tertiary center for rare adult–child liver disease. Nolwenn Laborde, Karl Barange, Chloé Girard, et al., Archives de Pédiatrie 2023. DOI: 10.1016/j.arcped.2023.08.012

Proenkephalin deletion in hematopoietic cells induces intestinal barrier failure resulting in clinical feature similarities with irritable bowel syndrome in mice. Xavier Mas‐Orea, Léa Rey, ..., Jean‐Paul Motta, ..., Frédérick Barreau, et al., Communications Biology 2023. DOI: 10.1038/s42003-023-05542-2

S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis. Liwen Deng, Flavia G. Costa, ..., Céline Deraison, ..., Nathalie Vergnolle, et al., Cell 2023. DOI: 10.1016/j.cell.2023.10.019

Differences in bone microarchitecture between genetic and secondary iron‐overload mouse models suggest a role for hepcidin deficiency in iron‐related osteoporosis. François Robin, Daniel Chappard, ..., Chloé Latour, ..., Marie‐Paule Roth, et al., The FASEB Journal 2023. DOI: 10.1096/fj.202301184r

TAGADA: a scalable pipeline to improve genome annotations with RNA-seq data. Cyril Kurylo, Cervin Guyomar, ..., Sarah Djebali, NAR Genomics and Bioinformatics 2023. DOI: 10.1093/nargab/lqad089

Alimentation sans gluten : quelles indications chez l’enfant ?. Chloé Girard, C. Barde, Emmanuel Mas, Journal de Pédiatrie et de Puériculture 2023. DOI: 10.1016/j.jpp.2023.09.003

Non-operative treatment of acute appendicitis in children: clinical efficacy of amoxicillin-clavulanic acid in a retrospective single-centre study. Clémence Picard, Olivier Abbo, ..., Damien Dubois, ..., Camille Bréhin, BMJ Paediatrics Open 2023. DOI: 10.1136/bmjpo-2023-001855

Scalable Nanopore sequencing of human genomes provides a comprehensive view of haplotype-resolved variation and methylation. Mikhail Kolmogorov, Kimberley J. Billingsley, ..., Jean Monlong, et al., Nature Methods 2023. DOI: 10.1038/s41592-023-01993-x

Postoperative ileus after digestive surgery: Network meta‐analysis of pharmacological intervention. Étienne Buscail, Thibault Planchamp, ..., Jean‐Paul Motta, Nathalie Vergnolle, Céline Deraison, et al., British Journal of Clinical Pharmacology 2023. DOI: 10.1111/bcp.15878

HlyF, an underestimated virulence factor of uropathogenic Escherichia coli. Camille V. Chagneau, Delphine Payros, ..., Carine Séguy, Clémence Massip, Priscilla Branchu, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, Clinical Microbiology and Infection 2023. DOI: 10.1016/j.cmi.2023.07.024

Accuracy of Serological Screening for the Diagnosis of Celiac Disease in Type 1 Diabetes Children. Chloé Girard, Aurélie De Percin, ..., Emmanuel Mas, Medicina 2023. DOI: 10.3390/medicina59071321

Oxygen concentration modulates colibactin production. Nadège Bossuet‐Greif, Cécile Guyonnet, Camille V. Chagneau, ..., Marie Pénary, ..., Priscilla Branchu, Éric Oswald, Jean‐Philippe Nougayrède, Gut Microbes 2023. DOI: 10.1080/19490976.2023.2222437

Daphnanes diterpenes from the latex of Hura crepitans L. and their PKCζ-dependent anti-proliferative activity on colorectal cancer cells. Elise Crossay, Valérie Jullian, ..., David Sagnat, ..., Étienne Buscail, ..., Céline Deraison, Claire Racaud‐Sultan, et al., Bioorganic & Medicinal Chemistry 2023. DOI: 10.1016/j.bmc.2023.117366

Nutrición enteral. Aurélie Bourchany, N. Laborde, ..., Emmanuel Mas, EMC - Pediatría 2023. DOI: 10.1016/s1245-1789(23)47710-4

A draft human pangenome reference. Wen‐Wei Liao, Mobin Asri, ..., Jean Monlong, et al., Nature 2023. DOI: 10.1038/s41586-023-05896-x

Pangenome graph construction from genome alignments with Minigraph-Cactus. Glenn Hickey, Jean Monlong, et al., Nature Biotechnology 2023. DOI: 10.1038/s41587-023-01793-w

Clinical decision-making training using the Script Concordance Test and simulation: A pilot study for pediatric residents. E. Baudou, Céline Guilbeau‐Frugier, ..., Emmanuel Mas, ..., Camille Bréhin, Archives de Pédiatrie 2023. DOI: 10.1016/j.arcped.2023.03.007

40 PERIPHERAL MEDIATORS INVOLVED IN SENSORY NEURONS SENSITIZATION IN IBD PATIENTS IN REMISSION: A WINDOW ON A PAR1-MEDIATED MECHANISM OF IBD-ASSOCIATED PAIN. Corinne Rolland, Perrine Rousset, ..., Étienne Buscail, ..., Céline Deraison, Nathalie Vergnolle, Gastroenterology 2023. DOI: 10.1016/s0016-5085(23)00987-3

Prevalence and characterization of the seven major serotypes of Shiga toxin-producing Escherichia coli (STEC) in veal calves slaughtered in France. Frédéric Auvray, Clémence Bièche-Terrier, ..., Éric Oswald, ..., Hubert Brugère, Veterinary Microbiology 2023. DOI: 10.1016/j.vetmic.2023.109754

Intestinal involvement in lupus: From pathophysiology to therapeutic perspectives. Caroline Carlé, Emmanuel Mas, Frédérick Barreau, Lupus 2023. DOI: 10.1177/09612033231155840

Enhancer/gene relationships: Need for more reliable genome-wide reference sets. Tristan Hoellinger, Camille Mestre, ..., Sarah Djebali, Frontiers in Bioinformatics 2023. DOI: 10.3389/fbinf.2023.1092853

A novel toxic effect of foodborne trichothecenes: The exacerbation of genotoxicity. Marion Garofalo, Delphine Payros, Marie Pénary, Éric Oswald, Jean‐Philippe Nougayrède, et al., Environmental Pollution 2022. DOI: 10.1016/j.envpol.2022.120625

Elafin and its precursor trappin‐2: What is their therapeutic potential for intestinal diseases?. Céline Deraison, Chrystelle Bonnart, ..., Nathalie Vergnolle, British Journal of Pharmacology 2022. DOI: 10.1111/bph.15985

Prenatal stress induces changes in PAR2- and M3-dependent regulation of colon primitive cells. Mathieu Berger, Laura Guiraud, ..., David Sagnat, ..., Nathalie Vergnolle, Céline Deraison, ..., Claire Racaud‐Sultan, American Journal of Physiology-Gastrointestinal and Liver Physiology 2022. DOI: 10.1152/ajpgi.00061.2022

Identification of bacterial lipopeptides as key players in IBS. Camille Petitfils, Sarah Maurel, ..., Frédéric Auvray, ..., Jean‐Paul Motta, Pauline Floch, ..., Éric Oswald, et al., Gut 2022. DOI: 10.1136/gutjnl-2022-328084

Uncoupling the Hsp90 and DnaK chaperone activities revealed the in vivo relevance of their collaboration in bacteria. Marie Corteggiani, Nadège Bossuet‐Greif, Jean‐Philippe Nougayrède, ..., Éric Oswald, et al., Proceedings of the National Academy of Sciences 2022. DOI: 10.1073/pnas.2201779119

High Fecal Prevalence of mcr-Positive Escherichia coli in Veal Calves at Slaughter in France. Maryse Michèle Um, Véronique Dupouy, ..., Frédéric Auvray, Éric Oswald, Hubert Brugère, et al., Antibiotics 2022. DOI: 10.3390/antibiotics11081071

Respiratory syncytial virus ribonucleoproteins hijack microtubule Rab11 dependent transport for intracellular trafficking. Gina Cosentino, Katherine Marougka, Aurore Desquesnes, et al., PLOS Pathogens 2022. DOI: 10.1371/journal.ppat.1010619

Distribution of Achromobacter Species in 12 French Cystic Fibrosis Centers in 2020 by a Retrospective MALDI-TOF MS Spectrum Analysis. Thomas Garrigos, Manon Dollat, ..., Cécile Gaudru, ..., Hélène Guet‐Revillet, et al., Journal of Clinical Microbiology 2022. DOI: 10.1128/jcm.02422-21

Screening for β-lactam resistance by penicillin G in the Streptococcus anginosus group challenged by rare strains with altered PBPs. Camille V. Chagneau, Orancie Alcouffe, Marion Grare, Éric Oswald, Clémence Massip, Journal of Antimicrobial Chemotherapy 2022. DOI: 10.1093/jac/dkac139

Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptor. Jean Personnaz, Enzo B. Piccolo, et al., Science Advances 2022. DOI: 10.1126/sciadv.abg9055

Persistent Circulation of Enterohemorrhagic Escherichia coli (EHEC) O157:H7 in Cattle Farms: Characterization of Enterohemorrhagic Escherichia coli O157:H7 Strains and Fecal Microbial Communities of Bovine Shedders and Non-shedders. Delphine Bibbal, Philippe Ruiz, ..., Frédéric Auvray, ..., Hubert Brugère, Frontiers in Veterinary Science 2022. DOI: 10.3389/fvets.2022.852475

Outer membrane vesicles produced by pathogenic strains of Escherichia coli block autophagic flux and exacerbate inflammasome activation. Laure David, Frédéric E. Taieb, Marie Pénary, ..., Éric Oswald, Autophagy 2022. DOI: 10.1080/15548627.2022.2054040

Short course of immune-suppressive doses of prednisolone, evaluated through a prospective double-masked placebo-controlled clinical trial in healthy Beagles, is associated with sustained modifications in renal, hydration, and electrolytic status. M.I. Mantelli, Béatrice B. Roques, ..., Nicolas Jousserand, ..., Armelle Diquélou, et al., American Journal of Veterinary Research 2022. DOI: 10.2460/ajvr.21.09.0150

Porto‐Sinusoidal Vascular Disease. Chloé Girard, Nolwenn Laborde, ..., Emmanuel Mas, et al., Journal of Pediatric Gastroenterology and Nutrition 2022. DOI: 10.1097/mpg.0000000000003445

Global population structure of the Serratia marcescens complex and identification of hospital-adapted lineages in the complex. Tomoyuki Ono, Itsuki Taniguchi, ..., Damien Dubois, Éric Oswald, et al., Microbial Genomics 2022. DOI: 10.1099/mgen.0.000793

Two Polyketides Intertwined in Complex Regulation: Posttranscriptional CsrA-Mediated Control of Colibactin and Yersiniabactin Synthesis in Escherichia coli. Nadine Rehm, Alexander Wallenstein, ..., Camille V. Chagneau, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, et al., mBio 2022. DOI: 10.1128/mbio.03814-21

The foodborne contaminant deoxynivalenol exacerbates DNA damage caused by a broad spectrum of genotoxic agents. Marion Garofalo, Delphine Payros, Éric Oswald, Jean‐Philippe Nougayrède, et al., Science of The Total Environment 2022. DOI: 10.1016/j.scitotenv.2022.153280

Postoperative ileus: A pharmacological perspective. Étienne Buscail, Céline Deraison, British Journal of Pharmacology 2022. DOI: 10.1111/bph.15800

Wild Boars as Reservoir of Highly Virulent Clone of Hybrid Shiga Toxigenic and Enterotoxigenic Escherichia coli Responsible for Edema Disease, France. Alexandre Perrat, Priscilla Branchu, ..., Hubert Brugère, Frédéric Auvray, Éric Oswald, Emerging Infectious Diseases 2022. DOI: 10.3201/eid2802.211491

Pangenomics enables genotyping of known structural variants in 5202 diverse genomes. Jouni Sirén, Jean Monlong, et al., Science 2021. DOI: 10.1126/science.abg8871

Revisiting definition and assessment of intestinal trans-epithelial passage. Hanna Ilchmann-Diounou, Marie Buléon, ..., Sandrine Ménard, Cellular and Molecular Life Sciences 2021. DOI: 10.1007/s00018-021-04000-8

Lyme neuroborreliosis in pediatrics: A retrospective, descriptive study in southwest France. Eulalie Garrabe, Damien Dubois, ..., Camille Bréhin, Archives de Pédiatrie 2021. DOI: 10.1016/j.arcped.2021.08.001

Multiform antimicrobial resistance from a metabolic mutation. Sarah M. Schrader, Hélène Botella, ..., Julien Vaubourgeix, Science Advances 2021. DOI: 10.1126/sciadv.abh2037

A Toxic Friend: Genotoxic and Mutagenic Activity of the Probiotic Strain Escherichia coli Nissle 1917. Jean‐Philippe Nougayrède, Camille V. Chagneau, Jean‐Paul Motta, Nadège Bossuet‐Greif, ..., Frédéric E. Taieb, ..., Éric Oswald, mSphere 2021. DOI: 10.1128/msphere.00624-21

Titanium dioxide particles from the diet: involvement in the genesis of inflammatory bowel diseases and colorectal cancer. Frédérick Barreau, Céline Tisseyre, Sandrine Ménard, et al., Particle and Fibre Toxicology 2021. DOI: 10.1186/s12989-021-00421-2

Peripheral Opioid Receptor Blockade Enhances Epithelial Damage in Piroxicam-Accelerated Colitis in IL-10-Deficient Mice. Xavier Mas‐Orea, Morgane Sébert, ..., Céline Deraison, Frédérick Barreau, et al., International Journal of Molecular Sciences 2021. DOI: 10.3390/ijms22147387

A condensate-hardening drug blocks RSV replication in vivo. Jennifer Risso-Ballester, Marie Galloux, ..., Aurore Desquesnes, et al., Nature 2021. DOI: 10.1038/s41586-021-03703-z

Functional abdominal pain disorders and patient- and parent-reported outcomes in children with inflammatory bowel disease in remission. Léa Chantal Tran, Laure Bridoux‐Henno, ..., Anne Laure Breton, Emmanuel Mas, et al., Digestive and Liver Disease 2021. DOI: 10.1016/j.dld.2021.05.034

Bi-allelic variants in IPO8 cause a connective tissue disorder associated with cardiovascular defects, skeletal abnormalities, and immune dysregulation. Alban C. Ziegler, Rémi Duclaux‐Loras, ..., Emmanuel Mas, Anne Laure Breton, et al., The American Journal of Human Genetics 2021. DOI: 10.1016/j.ajhg.2021.04.020

Insights into the acquisition of the pks island and production of colibactin in the Escherichia coli population. Frédéric Auvray, Alexandre Perrat, ..., Camille V. Chagneau, Nadège Bossuet‐Greif, Clémence Massip, Hubert Brugère, Jean‐Philippe Nougayrède, ..., Priscilla Branchu, ..., Éric Oswald, Microbial Genomics 2021. DOI: 10.1099/mgen.0.000579

SHP2 drives inflammation-triggered insulin resistance by reshaping tissue macrophage populations. Romain Paccoud, Céline Saint-Laurent, ..., Jean Personnaz, et al., Science Translational Medicine 2021. DOI: 10.1126/scitranslmed.abe2587

Mycobacterium chimaera Genomics With Regard to Epidemiological and Clinical Investigations Conducted for an Open Chest Postsurgical Mycobacterium chimaera Infection Outbreak. Emmanuel Lecorché, Côme Daniau, ..., Laurent Cavalié, ..., Marion Grare, Hélène Guet‐Revillet, et al., Open Forum Infectious Diseases 2021. DOI: 10.1093/ofid/ofab192

Insights into evolution and coexistence of the colibactin- and yersiniabactin secondary metabolite determinants in enterobacterial populations. Haleluya Tesfaye Wami, Alexander Wallenstein, ..., Éric Oswald, et al., Microbial Genomics 2021. DOI: 10.1099/mgen.0.000577

Epithelial production of elastase is increased in inflammatory bowel disease and causes mucosal inflammation. Jean‐Paul Motta, Corinne Rolland, Anissa Edir, ..., David Sagnat, Chrystelle Bonnart, Perrine Rousset, Laura Guiraud, ..., Emmanuel Mas, ..., Étienne Buscail, ..., Nathalie Vergnolle, Céline Deraison, Mucosal Immunology 2021. DOI: 10.1038/s41385-021-00375-w

Uropathogenic E. coli induces DNA damage in the bladder. Camille V. Chagneau, Clémence Massip, Nadège Bossuet‐Greif, ..., Jean‐Paul Motta, ..., Marie‐Paule Roth, Hélène Coppin, ..., Jean‐Philippe Nougayrède, Éric Oswald, PLOS Pathogens 2021. DOI: 10.1371/journal.ppat.1009310

Colitis Linked to Endoplasmic Reticulum Stress Induces Trypsin Activity Affecting Epithelial Functions. Núria Solà Tapias, Alexandre Denadai‐Souza, ..., Anissa Edir, ..., Emmanuel Mas, ..., Céline Deraison, Chrystelle Bonnart, Nathalie Vergnolle, Frédérick Barreau, Journal of Crohn's and Colitis 2021. DOI: 10.1093/ecco-jcc/jjab035

Next-Generation Cancer Biomarkers: Extracellular Vesicle DNA as a Circulating Surrogate of Tumor DNA. Samuel Amintas, V. Vendrely, ..., Étienne Buscail, Frontiers in Cell and Developmental Biology 2021. DOI: 10.3389/fcell.2020.622048

GSK3β, a Master Kinase in the Regulation of Adult Stem Cell Behavior. Claire Racaud‐Sultan, Nathalie Vergnolle, Cells 2021. DOI: 10.3390/cells10020225

The Polyphosphate Kinase of Escherichia coli Is Required for Full Production of the Genotoxin Colibactin. Min Tang-Fichaux, Camille V. Chagneau, Nadège Bossuet‐Greif, Jean‐Philippe Nougayrède, Éric Oswald, Priscilla Branchu, mSphere 2020. DOI: 10.1128/msphere.01195-20

Increased Mucosal Thrombin is Associated with Crohn’s Disease and Causes Inflammatory Damage through Protease-activated Receptors Activation. Jean‐Paul Motta, Simone Palese, ..., Perrine Rousset, David Sagnat, Laura Guiraud, Anissa Edir, Carine Séguy, ..., Éric Oswald, ..., Céline Deraison, Nathalie Vergnolle, Journal of Crohn's and Colitis 2020. DOI: 10.1093/ecco-jcc/jjaa229

Nonredundant functions of Mycobacterium tuberculosis chaperones promote survival under stress. Alexa P. Harnagel, Landys A. Lopez Quezada, ..., Julien Vaubourgeix, et al., Molecular Microbiology 2020. DOI: 10.1111/mmi.14615

Bacteria-derived long chain fatty acid exhibits anti-inflammatory properties in colitis. Julien Pujo, Camille Petitfils, ..., Frédérick Barreau, ..., Éric Oswald, et al., Gut 2020. DOI: 10.1136/gutjnl-2020-321173

Expanded encyclopaedias of DNA elements in the human and mouse genomes. Federico Abascal, Reyes Acosta, ..., Sarah Djebali, et al., Nature 2020. DOI: 10.1038/s41586-020-2493-4

Reduced Intestinal Inflammation With Lumacaftor/Ivacaftor in Adolescents With Cystic Fibrosis. Candice Tétard, Marie Mittaine, ..., Emmanuel Mas, et al., Journal of Pediatric Gastroenterology and Nutrition 2020. DOI: 10.1097/mpg.0000000000002864

The Genotoxin Colibactin Shapes Gut Microbiota in Mice. Sophie Tronnet, Pauline Floch, ..., Éric Oswald, mSphere 2020. DOI: 10.1128/msphere.00589-20

Biology of antimicrobial resistance and approaches to combat it. Sarah M. Schrader, Julien Vaubourgeix, et al., Science Translational Medicine 2020. DOI: 10.1126/scitranslmed.aaz6992

Characterization of Human Colon Organoids From Inflammatory Bowel Disease Patients. Emilie d'Aldebert, Muriel Quaranta, ..., Claire Racaud‐Sultan, Emmanuel Mas, Céline Deraison, Nathalie Vergnolle, Frontiers in Cell and Developmental Biology 2020. DOI: 10.3389/fcell.2020.00363

A fully human anti-BMP6 antibody reduces the need for erythropoietin in rodent models of the anemia of chronic disease. Verena Petzer, Piotr Tymoszuk, ..., Léon Kautz, et al., Blood 2020. DOI: 10.1182/blood.2019004653

The Interplay Between Genetic Risk Factors and Proteolytic Dysregulation in the Pathophysiology of Inflammatory Bowel Disease. Núria Solà-Tapias, Nathalie Vergnolle, ..., Frédérick Barreau, Journal of Crohn's and Colitis 2020. DOI: 10.1093/ecco-jcc/jjaa033

Genotyping structural variants in pangenome graphs using the vg toolkit. Glenn Hickey, David Heller, Jean Monlong, et al., Genome Biology 2020. DOI: 10.1186/s13059-020-1941-7

Multi-species annotation of transcriptome and chromatin structure in domesticated animals. Sylvain Foissac, Sarah Djebali, et al., BMC Biology 2019. DOI: 10.1186/s12915-019-0726-5

Nod2 Protects the Gut From Experimental Colitis Spreading to Small Intestine. Ziad Al Nabhani, Dominique D. Berrebi, ..., Frédérick Barreau, et al., Journal of Crohn's and Colitis 2019. DOI: 10.1093/ecco-jcc/jjz196

Persistent Mycobacterium tuberculosis infection in mice requires PerM for successful cell division. Ruojun Wang, Kaj M. Kreutzfeldt, ..., Julien Vaubourgeix, et al., eLife 2019. DOI: 10.7554/elife.49570

Deciphering the interplay between the genotoxic and probiotic activities of Escherichia coli Nissle 1917. Clémence Massip, Priscilla Branchu, Nadège Bossuet‐Greif, Camille V. Chagneau, ..., Damien Dubois, Jean‐Philippe Nougayrède, Éric Oswald, PLOS Pathogens 2019. DOI: 10.1371/journal.ppat.1008029

Sexual dimorphism in PAR2-dependent regulation of primitive colonic cells. Julie Noguerol, Pierre-Jean Roustan, ..., Laura Guiraud, David Sagnat, Anissa Edir, Chrystelle Bonnart, ..., Céline Deraison, Nathalie Vergnolle, Claire Racaud‐Sultan, Biology of Sex Differences 2019. DOI: 10.1186/s13293-019-0262-6

Active thrombin produced by the intestinal epithelium controls mucosal biofilms. Jean‐Paul Motta, Alexandre Denadai‐Souza, David Sagnat, Laura Guiraud, Anissa Edir, Chrystelle Bonnart, ..., Perrine Rousset, ..., Carine Séguy, ..., Éric Oswald, ..., Céline Deraison, Nathalie Vergnolle, Nature Communications 2019. DOI: 10.1038/s41467-019-11140-w

A variant erythroferrone disrupts iron homeostasis in SF3B1 -mutated myelodysplastic syndrome. Sabrina Bondu, Anne‐Sophie Alary, ..., Léon Kautz, et al., Science Translational Medicine 2019. DOI: 10.1126/scitranslmed.aav5467

Intestinal Bile Acids Induce a Morphotype Switch in Vancomycin-Resistant Enterococcus that Facilitates Intestinal Colonization. Peter T. McKenney, Jinyuan Yan, Julien Vaubourgeix, et al., Cell Host & Microbe 2019. DOI: 10.1016/j.chom.2019.03.008

Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2. Alberto Caminero, Justin L. McCarville, ..., Céline Deraison, ..., Nathalie Vergnolle, et al., Nature Communications 2019. DOI: 10.1038/s41467-019-09037-9

Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition. Elaine A. Ballinger, John Mosior, ..., Julien Vaubourgeix, et al., Science 2019. DOI: 10.1126/science.aau8959

Building Walls: Work That Never Ends. Hélène Botella, Julien Vaubourgeix, Trends in Microbiology 2018. DOI: 10.1016/j.tim.2018.11.006

Erythroferrone is not required for the glucoregulatory and hematologic effects of chronic erythropoietin treatment in mice. Richard Coffey, Ugo Sardo, Léon Kautz, et al., Physiological Reports 2018. DOI: 10.14814/phy2.13890

Shift in skin microbiota of Western European women across aging. Romain Jugé, Pauline Rouaud, ..., Marie‐Paule Roth, Hélène Coppin, et al., Journal of Applied Microbiology 2018. DOI: 10.1111/jam.13929

Diagnostic Yield of Next-generation Sequencing in Very Early-onset Inflammatory Bowel Diseases: A Multicentre Study. Fabienne Charbit‐Henrion, Marianna Parlato, ..., Anne Laure Breton, ..., Emmanuel Mas, et al., Journal of Crohn's and Colitis 2018. DOI: 10.1093/ecco-jcc/jjy068

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics. Alvaro Barbeira, Scott P. Dickinson, ..., Jean Monlong, et al., Nature Communications 2018. DOI: 10.1038/s41467-018-03621-1

The Colibactin Genotoxin Generates DNA Interstrand Cross-Links in Infected Cells. Nadège Bossuet‐Greif, Julien Vignard, Frédéric E. Taieb, ..., Damien Dubois, ..., Éric Oswald, Jean‐Philippe Nougayrède, mBio 2018. DOI: 10.1128/mbio.02393-17

Targeting the Proteostasis Network for Mycobacterial Drug Discovery. Tania J. Lupoli, Julien Vaubourgeix, et al., ACS Infectious Diseases 2018. DOI: 10.1021/acsinfecdis.7b00231

Identification of an analgesic lipopeptide produced by the probiotic Escherichia coli strain Nissle 1917. Teresa Pérez, Julien Pujo, ..., Frédérick Barreau, ..., Éric Oswald, et al., Nature Communications 2017. DOI: 10.1038/s41467-017-01403-9

Deletion of BMP6 worsens the phenotype of HJV-deficient mice and attenuates hepcidin levels reached after LPS challenge. Chloé Latour, Céline Besson‐Fournier, ..., Delphine Meynard, Marie‐Paule Roth, Hélène Coppin, Blood 2017. DOI: 10.1182/blood-2017-07-795658

Oral Administration of the Probiotic Strain Escherichia coli Nissle 1917 Reduces Susceptibility to Neuroinflammation and Repairs Experimental Autoimmune Encephalomyelitis-Induced Intestinal Barrier Dysfunction. Thomas Sécher, Sahar Kassem, ..., Frédérick Barreau, Éric Oswald, et al., Frontiers in Immunology 2017. DOI: 10.3389/fimmu.2017.01096

Distinct Spatiotemporal Dynamics of Peptidoglycan Synthesis between Mycobacterium smegmatis and Mycobacterium tuberculosis. Hélène Botella, Guangli Yang, ..., Julien Vaubourgeix, mBio 2017. DOI: 10.1128/mbio.01183-17

Immunoassay for human serum erythroferrone. Tomas Ganz, Grace Jung, ..., Léon Kautz, et al., Blood 2017. DOI: 10.1182/blood-2017-04-777987

The Food Contaminant Deoxynivalenol Exacerbates the Genotoxicity of Gut Microbiota. Delphine Payros, Ulrich Dobrindt, ..., Éric Oswald, et al., mBio 2017. DOI: 10.1128/mbio.00007-17

Protectin D1 n-3 DPA and resolvin D5 n-3 DPA are effectors of intestinal protection. Thomas Gobbetti, Jesmond Dalli, ..., Nathalie Vergnolle, Céline Deraison, et al., Proceedings of the National Academy of Sciences 2017. DOI: 10.1073/pnas.1617290114

Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death. Laure Botella, Julien Vaubourgeix, et al., Nature Communications 2017. DOI: 10.1038/ncomms14731

An atlas of human long non-coding RNAs with accurate 5′ ends. Chung-Chau Hon, Jordan A. Ramilowski, ..., Sarah Djebali, et al., Nature 2017. DOI: 10.1038/nature21374

Erythroferrone and matriptase‐2 independently regulate hepcidin expression. Sharraya Aschemeyer, Victoria R. Gabayan, ..., Léon Kautz, American Journal of Hematology 2017. DOI: 10.1002/ajh.24672

Epithelial expression and function of trypsin-3 in irritable bowel syndrome. Claire Rolland-Fourcade, Alexandre Denadai‐Souza, ..., Jean‐Paul Motta, ..., Céline Deraison, Nathalie Vergnolle, Gut 2017. DOI: 10.1136/gutjnl-2016-312094

Mycobacterium tuberculosis protease MarP activates a peptidoglycan hydrolase during acid stress. Hélène Botella, Julien Vaubourgeix, et al., The EMBO Journal 2017. DOI: 10.15252/embj.201695028

Hepcidin upregulation by inflammation is independent of Smad1/5/8 signaling by activin B. Céline Besson‐Fournier, Aurélie Gineste, Chloé Latour, ..., Delphine Meynard, ..., Éric Oswald, Hélène Coppin, Marie‐Paule Roth, Blood 2016. DOI: 10.1182/blood-2016-10-748541

Endogenous analgesia mediated by CD4+ T lymphocytes is dependent on enkephalins in mice. Lilian Basso, Jérôme Boué, ..., Nathalie Vergnolle, Céline Deraison, et al., Journal of Neuroinflammation 2016. DOI: 10.1186/s12974-016-0591-x

Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice. Antonella Nai, Aude Rubio, ..., Chloé Latour, Céline Besson‐Fournier, ..., Hélène Coppin, Marie‐Paule Roth, ..., Delphine Meynard, Blood 2016. DOI: 10.1182/blood-2015-11-681494

Apelin targets gut contraction to control glucose metabolism via the brain. Audren Fournel, Anne Drougard, ..., Perrine Rousset, ..., Nathalie Vergnolle, et al., Gut 2015. DOI: 10.1136/gutjnl-2015-310230

Retrograde Trafficking Inhibitor of Shiga Toxins Reduces Morbidity and Mortality of Mice Infected with Enterohemorrhagic Escherichia coli. Thomas Sécher, Ayaka Shima, ..., Éric Oswald, Antimicrobial Agents and Chemotherapy 2015. DOI: 10.1128/aac.00455-15

Disruption of an M. tuberculosis Membrane Protein Causes a Magnesium-dependent Cell Division Defect and Failure to Persist in Mice. Nichole Goodsmith, Xinzheng Victor Guo, ..., Julien Vaubourgeix, et al., PLOS Pathogens 2015. DOI: 10.1371/journal.ppat.1004645

Stressed Mycobacteria Use the Chaperone ClpB to Sequester Irreversibly Oxidized Proteins Asymmetrically Within and Between Cells. Julien Vaubourgeix, Gang Lin, et al., Cell Host & Microbe 2015. DOI: 10.1016/j.chom.2014.12.008

The Genotoxin Colibactin Exacerbates Lymphopenia and Decreases Survival Rate in Mice Infected With Septicemic Escherichia coli. Ingrid Marcq, P. Martin, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, Journal of Infectious Diseases 2014. DOI: 10.1093/infdis/jiu071

Interplay between Siderophores and Colibactin Genotoxin Biosynthetic Pathways in Escherichia coli. Patricia Martín, Ingrid Marcq, ..., Marie Pénary, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, PLoS Pathogens 2013. DOI: 10.1371/journal.ppat.1003437

N,C-Capped Dipeptides with Selectivity for Mycobacterial Proteasome over Human Proteasomes: Role of S3 and S1 Binding Pockets. Gang Lin, Tamutenda Chidawanyika, ..., Julien Vaubourgeix, et al., Journal of the American Chemical Society 2013. DOI: 10.1021/ja400021x

A Common Mechanism of Inhibition of the Mycobacterium tuberculosis Mycolic Acid Biosynthetic Pathway by Isoxyl and Thiacetazone. Anna E. Grzegorzewicz, Jana Korduláková, ..., Julien Vaubourgeix, et al., Journal of Biological Chemistry 2012. DOI: 10.1074/jbc.m112.400994

Deciphering sulfoglycolipids of Mycobacterium tuberculosis. Emilie Layre, Diane Cala‐De Paepe, ..., Julien Vaubourgeix, et al., Journal of Lipid Research 2011. DOI: 10.1194/jlr.m013482

Pathogenic Bacteria Target NEDD8-Conjugated Cullins to Hijack Host-Cell Signaling Pathways. Grégory Jubelin, Frédéric E. Taieb, ..., Marie Pénary, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, PLoS Pathogens 2010. DOI: 10.1371/journal.ppat.1001128

Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells. Gabriel Cuevas Ramos, Claude R. Petit, ..., Éric Oswald, Jean‐Philippe Nougayrède, Proceedings of the National Academy of Sciences 2010. DOI: 10.1073/pnas.1001261107

Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ. Jichan Jang, Alexandre Stella, ..., Julien Vaubourgeix, et al., Microbiology 2010. DOI: 10.1099/mic.0.038133-0

S-Adenosyl-N-decyl-aminoethyl, a Potent Bisubstrate Inhibitor of Mycobacterium tuberculosis Mycolic Acid Methyltransferases. Julien Vaubourgeix, F. Bardou, et al., Journal of Biological Chemistry 2009. DOI: 10.1074/jbc.m809599200

Foamy Macrophages from Tuberculous Patients’ Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence. Pascale Peyron, Julien Vaubourgeix, et al., PLoS Pathogens 2008. DOI: 10.1371/journal.ppat.1000204

Escherichia coli Induces DNA Double-Strand Breaks in Eukaryotic Cells. Jean‐Philippe Nougayrède, Stefan Homburg, Frédéric E. Taieb, ..., Éric Oswald, Science 2006. DOI: 10.1126/science.1127059

Role of Tir and Intimin in the Virulence of Rabbit EnteropathogenicEscherichia coliSerotype O103:H2. Olivier Marchès, Jean‐Philippe Nougayrède, ..., Éric Oswald, Infection and Immunity 2000. DOI: 10.1128/iai.68.4.2171-2182.2000

A new cytolethal distending toxin (CDT) from Escherichia coli producing CNF2 blocks HeLa cell division in G2/M phase. Sylvie Y. Pérès, Olivier Marchès, ..., Jean‐Philippe Nougayrède, ..., Éric Oswald, Molecular Microbiology 1997. DOI: 10.1046/j.1365-2958.1997.4181785.x