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CONTACTS
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EQUIPE 4 : METABOLISME DUE FER: DE LA REGULATION A LA THERAPIE
TEAM 4 : IRON METABOLISM:FROM REGULATION TO THERAPY |
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Mini CVEDUCATION
RESEARCH RELATED EXPERIENCE
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expertisePCR quantitative, western blot, techniques d’histologie et d’immuno fluorescence, microscopie confocale.
Quantitative PCR, western blot, histology , immunofluorescence, confocal microscopy |
RECHERCHE/PROJET RESEARCH/PROJECT
Régulation du métabolisme du fer lors des processus infectieux et inflammatoires.
Iron metabolism regulation during inflammatory and infectious processes
Iron metabolism regulation during inflammatory and infectious processes
PRODUCTION SCIENTIFIQUE SCIENTIFIC PRODUCTION
Differing impact of the deletion of hemochromatosis-associated molecules HFE and transferrin receptor-2 on the iron phenotype of mice lacking bone morphogenetic protein 6 or hemojuvelin.Latour C, Besson-Fournier C, Meynard D, Silvestri L, Gourbeyre O, Aguilar-Martinez P, Schmidt PJ, Fleming MD, Roth MP, Coppin H.
Hepatology. 2016 Jan;63(1):126-37.
Evidence for IL-6/STAT3-independent induction of lipocalin-2 in the liver of mice infected with Escherichia coli.
Gineste A, Martin P, Oswald E, Coppin H, Roth MP.
Hepatology. 2016 Feb;63(2):673-4
Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin.
Latour C, Kautz L, Besson-Fournier C, Island ML, Canonne-Hergaux F, Loréal O, Ganz T, Coppin H, Roth MP.
Hepatology. 2014 Feb;59(2):683-94.
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Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling.
Besson-Fournier C, Latour C, Kautz L, Bertrand J, Ganz T, Roth MP, Coppin H.
Blood. 2012 Jul 12;120(2):431-9
Iron overload induces BMP6 expression in the liver but not in the duodenum.
Kautz L, Besson-Fournier C, Meynard D, Latour C, Roth MP, Coppin H.
Haematologica. 2011 Feb;96(2):199-203.
Lack of the bone morphogenetic protein BMP6 induces massive iron overload.
Meynard D, Kautz L, Darnaud V, Canonne-Hergaux F, Coppin H, Roth MP.
Nat Genet. 2009 Apr;41(4):478-81.
BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression.
Kautz L, Meynard D, Besson-Fournier C, Darnaud V, Al Saati T, Coppin H, Roth MP.
Blood. 2009 Sep 17;114(12):2515-20
Hepatology. 2016 Jan;63(1):126-37.
Evidence for IL-6/STAT3-independent induction of lipocalin-2 in the liver of mice infected with Escherichia coli.
Gineste A, Martin P, Oswald E, Coppin H, Roth MP.
Hepatology. 2016 Feb;63(2):673-4
Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin.
Latour C, Kautz L, Besson-Fournier C, Island ML, Canonne-Hergaux F, Loréal O, Ganz T, Coppin H, Roth MP.
Hepatology. 2014 Feb;59(2):683-94.
.
Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling.
Besson-Fournier C, Latour C, Kautz L, Bertrand J, Ganz T, Roth MP, Coppin H.
Blood. 2012 Jul 12;120(2):431-9
Iron overload induces BMP6 expression in the liver but not in the duodenum.
Kautz L, Besson-Fournier C, Meynard D, Latour C, Roth MP, Coppin H.
Haematologica. 2011 Feb;96(2):199-203.
Lack of the bone morphogenetic protein BMP6 induces massive iron overload.
Meynard D, Kautz L, Darnaud V, Canonne-Hergaux F, Coppin H, Roth MP.
Nat Genet. 2009 Apr;41(4):478-81.
BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression.
Kautz L, Meynard D, Besson-Fournier C, Darnaud V, Al Saati T, Coppin H, Roth MP.
Blood. 2009 Sep 17;114(12):2515-20
