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PROFESSEUR D'UNIVERSITE (PR)
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University professor 

claude KNAUF

contact

​00 33 (0)5 62 74 45 21

EQUIPE 3 : INTERACTIONS NEURO-IMMUNES ​INTESTINALES
TEAM 3 : INTESTINAL NEURO-IMMUNE INTERACTIONS

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Mini CV

Professor of physiology University of Toulouse​
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expertise

• Genetic and  nutritional obese/diabetic mouse models
  
• Animal surgery (ig, iv, icv)
  
• Real-time measurement of reactive oxygen and nitrogen species
  
• Intestinal contraction (telemetry, isotonic)
  
• Molecular and cellular biology (Western Blot, qPCR,…)
  
• Glucose metabolism (OGTT, ITT, clamp)
  
• Primary culture of enteric neurons
  

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Recherche/projet  research/project

Enteric Nervous System and Glucose Metabolism 
Determine the impact of the gut-to-brain axis on glucose metabolism  

Production scientifique scientific production 

• Fournel A, Drougard A, Duparc T, Marlin A, Brierley SM, Castro J, Le-Gonidec S, Masri B, Colom A, Lucas A, Rousset P, Cenac N, Vergnolle N, Valet P, Cani PD, Knauf C. Apelin targets gut contraction to control glucose metabolism via the brain. Gut. 2016

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• Drougard A, Duparc T, Brenachot X, Carneiro L, Gouazé A, Fournel A, Geurts L, Cadoudal T, Prats AC, Pénicaud L, Vieau D, Lesage J, Leloup C, Benani A, Cani PD, Valet P, Knauf C. Hypothalamic apelin/reactive oxygen species signaling controls hepatic glucose metabolism in the onset of diabetes. Antioxidants and Redox Signaling. 2014, 20(4):557-573.