Jean-Philippe Nougayrède |
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EQUIPE 2 : PATHOGÉNIE ET COMMENSALISME DES ENTEROBACTÉRIES
TEAM 2 : PATHOGENESIS AND COMMENSALISM OF ENTEROBACTERIA |
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Mini CV
- 2000 PhD of Microbiology, Lyon University
- 2000-2003 Post-doc, Baltimore, MD, USA
- 2003-2006 Post-doc, INRA, Toulouse
- 2006 Junior permanent researcher (CR2)
- 2010 Senior permanent researcher (CR1)
- 2021 Research director (DR2)
Recherche/projet research/project
Mode of action of bacterial toxins
Mode d'action des toxines bactériennes
Mode d'action des toxines bactériennes
Production scientifique scientific production
Auvray F, Perrat A, Arimizu Y, Chagneau CV, Bossuet-Greif N, Massip C, Brugère H, Nougayrède JP, Hayashi T, Branchu P, Ogura Y, Oswald E. Insights into the acquisition of the pks island and production of colibactin in the Escherichia coli population. Microb Genom. 2021 May;7(5).
Chagneau CV, Massip C, Bossuet-Greif N, Fremez C, Motta JP, Shima A, Besson C, Le Faouder P, Cénac N, Roth MP, Coppin H, Fontanié M, Martin P, Nougayrède JP, Oswald E. Uropathogenic E. coli induces DNA damage in the bladder. PLoS Pathog. 2021 Feb 25;17(2):e1009310.
Tang-Fichaux M, Chagneau CV, Bossuet-Greif N, Nougayrède JP, Oswald É, Branchu P. The Polyphosphate Kinase of Escherichia coli Is Required for Full Production of the Genotoxin Colibactin. mSphere. 2020 Dec 16;5(6):e01195-20.
Wallenstein A, Rehm N, Brinkmann M, Selle M, Bossuet-Greif N, Sauer D, Bunk B, Spröer C, Wami HT, Homburg S, von Bünau R, König S, Nougayrède JP, Overmann J, Oswald E, Müller R, Dobrindt U. ClbR Is the Key Transcriptional Activator of Colibactin Gene Expression in Escherichia coli. mSphere. 2020 Jul 15;5(4):e00591-20
Chagneau CV, Garcie C, Bossuet-Greif N, Tronnet S, Brachmann AO, Piel J, Nougayrède JP, Martin P, Oswald E. The Polyamine Spermidine Modulates the Production of the Bacterial Genotoxin Colibactin. mSphere. 2019 Oct 2;4(5):e00414-19.
Massip C, Branchu P, Bossuet-Greif N, Chagneau CV, Gaillard D, Martin P, Boury M, Sécher T, Dubois D, Nougayrède JP, Oswald E. Deciphering the interplay between the genotoxic and probiotic activities of Escherichia coli Nissle 1917. PLoS Pathog. 2019 Sep 23;15(9):e1008029.
Bossuet-Greif N, Vignard J, Taieb F, Mirey G, Dubois D, Petit C, Oswald E, Nougayrède JP. The Colibactin Genotoxin Generates DNA Interstrand Cross-Links in Infected Cells. mBio. 2018 Mar 20;9(2). pii: e02393-17.
Garcie C., Tronnet S., Garénaux A., McCarthy A.J., Brachmann A.O., Pénary M, Houle S., Nougayrède J.P., Piel J., Taylor P.W., Dozois C.M., Genevaux P., Oswald E. and Martin P. The stress-responsive Hsp90 chaperone is required for the production of genotoxin and siderophore by pathogenic Escherichia coli. J Infect Dis. 2016 Sep 15;214(6):916-24.
Taieb F, Petit C, Nougayrède JP, Oswald E. The Enterobacterial Genotoxins: Cytolethal Distending Toxin and Colibactin. EcoSal Plus. 2016 Jul;7(1).
Bossuet-Greif N, Dubois D, Petit C, Tronnet S, Martin P, Bonnet R, Oswald E, Nougayrède JP. Escherichia coli ClbS is a colibactin resistance protein. Mol Microbiol. 2016 Mar;99(5):897-908.
Murase K, Martin P, Porcheron G, Houle S, Helloin E, Penary M, Nougayrede JP, Dozois CM, Hayashi T, Oswald E. HlyF Produced by Extraintestinal Pathogenic Escherichia coli Is a Virulence Factor That Regulates Outer Membrane Vesicle Biogenesis. J Infect Dis. 2016 Mar 1;213(5):856-65.
Chagneau CV, Massip C, Bossuet-Greif N, Fremez C, Motta JP, Shima A, Besson C, Le Faouder P, Cénac N, Roth MP, Coppin H, Fontanié M, Martin P, Nougayrède JP, Oswald E. Uropathogenic E. coli induces DNA damage in the bladder. PLoS Pathog. 2021 Feb 25;17(2):e1009310.
Tang-Fichaux M, Chagneau CV, Bossuet-Greif N, Nougayrède JP, Oswald É, Branchu P. The Polyphosphate Kinase of Escherichia coli Is Required for Full Production of the Genotoxin Colibactin. mSphere. 2020 Dec 16;5(6):e01195-20.
Wallenstein A, Rehm N, Brinkmann M, Selle M, Bossuet-Greif N, Sauer D, Bunk B, Spröer C, Wami HT, Homburg S, von Bünau R, König S, Nougayrède JP, Overmann J, Oswald E, Müller R, Dobrindt U. ClbR Is the Key Transcriptional Activator of Colibactin Gene Expression in Escherichia coli. mSphere. 2020 Jul 15;5(4):e00591-20
Chagneau CV, Garcie C, Bossuet-Greif N, Tronnet S, Brachmann AO, Piel J, Nougayrède JP, Martin P, Oswald E. The Polyamine Spermidine Modulates the Production of the Bacterial Genotoxin Colibactin. mSphere. 2019 Oct 2;4(5):e00414-19.
Massip C, Branchu P, Bossuet-Greif N, Chagneau CV, Gaillard D, Martin P, Boury M, Sécher T, Dubois D, Nougayrède JP, Oswald E. Deciphering the interplay between the genotoxic and probiotic activities of Escherichia coli Nissle 1917. PLoS Pathog. 2019 Sep 23;15(9):e1008029.
Bossuet-Greif N, Vignard J, Taieb F, Mirey G, Dubois D, Petit C, Oswald E, Nougayrède JP. The Colibactin Genotoxin Generates DNA Interstrand Cross-Links in Infected Cells. mBio. 2018 Mar 20;9(2). pii: e02393-17.
Garcie C., Tronnet S., Garénaux A., McCarthy A.J., Brachmann A.O., Pénary M, Houle S., Nougayrède J.P., Piel J., Taylor P.W., Dozois C.M., Genevaux P., Oswald E. and Martin P. The stress-responsive Hsp90 chaperone is required for the production of genotoxin and siderophore by pathogenic Escherichia coli. J Infect Dis. 2016 Sep 15;214(6):916-24.
Taieb F, Petit C, Nougayrède JP, Oswald E. The Enterobacterial Genotoxins: Cytolethal Distending Toxin and Colibactin. EcoSal Plus. 2016 Jul;7(1).
Bossuet-Greif N, Dubois D, Petit C, Tronnet S, Martin P, Bonnet R, Oswald E, Nougayrède JP. Escherichia coli ClbS is a colibactin resistance protein. Mol Microbiol. 2016 Mar;99(5):897-908.
Murase K, Martin P, Porcheron G, Houle S, Helloin E, Penary M, Nougayrede JP, Dozois CM, Hayashi T, Oswald E. HlyF Produced by Extraintestinal Pathogenic Escherichia coli Is a Virulence Factor That Regulates Outer Membrane Vesicle Biogenesis. J Infect Dis. 2016 Mar 1;213(5):856-65.
