MATTEO Serino |
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EQUIPE 2 : PATHOGÉNIE ET COMMENSALISME DES ENTEROBACTÉRIES
TEAM 2 : PATHOGENESIS AND COMMENSALISM OF ENTEROBACTERIA |
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Mini CV
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expertiseDNA extraction from mouse tail, intraperitoneal glucose/insulin/pyruvate tolerance test, retro-orbital cavity/tail-vein injection, mouse genotyping by Polymerase Chain Reaction (PCR), Enzyme-Linked Immunosorbent Assay (ELISA) and other biochemical assays, Western Blots, RNA/microRNA extraction and Real-Time PCR, Immunohistochemistry, mouse dissection, organ collection and cryopreservation, cell-culture, mice handling, management and establishment of mouse colonies, genetic background purification by crossing multiple generations. Establishment of axenic mice platform from scratch; microbial analyses for axenic mice status checking; preparation of bacterial suspension from mice/human stool; colonization/humanization of axenic mice; DNA extraction from mouse/human feces; metagenomic data management and analysis.
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Recherche/projet research/project
ENTEROBACTERIAL INFECTIONS AND DYSBIOSIS IN METABOLIC DISEASES, GUT INFLAMMATION AND CANCER
Production scientifique scientific production
Blasco-Baque V, Coupé B, Fabre A, Handgraaf S, Gourdy P, Arnal JF, Courtney M, Schuster-Klein C, Guardiola B, Tercé F, Burcelin R, Serino M.
Associations between hepatic miRNA expression, liver triacylglycerols and gut microbiota during metabolic adaptation to high-fat diet in mice.
Diabetologia. 2017 Apr;60(4):690-700.
Nicolas S, Blasco-Baque V, Fournel A, Gilleron J, Klopp P, Waget A, Ceppo F, Marlin A, Padmanabhan R, Iacovoni JS, Tercé F, Cani PD, Tanti JF, Burcelin R, Knauf C, Cormont M, Serino M. Transfer of dysbiotic gut microbiota has beneficial effects on host liver metabolism. Mol Syst Biol. 2017 Mar 16;13(3):921.
Lelouvier B, Servant F, Païssé S, Brunet AC, Benyahya S, Serino M, Valle C, Ortiz MR, Puig J, Courtney M, Federici M, Fernández-Real JM, Burcelin R, Amar J. Changes in blood microbiota profiles associated with liver fibrosis in obese patients: A pilot analysis. Hepatology. 2016 Dec;64(6):2015-2027.
Associations between hepatic miRNA expression, liver triacylglycerols and gut microbiota during metabolic adaptation to high-fat diet in mice.
Diabetologia. 2017 Apr;60(4):690-700.
Nicolas S, Blasco-Baque V, Fournel A, Gilleron J, Klopp P, Waget A, Ceppo F, Marlin A, Padmanabhan R, Iacovoni JS, Tercé F, Cani PD, Tanti JF, Burcelin R, Knauf C, Cormont M, Serino M. Transfer of dysbiotic gut microbiota has beneficial effects on host liver metabolism. Mol Syst Biol. 2017 Mar 16;13(3):921.
Lelouvier B, Servant F, Païssé S, Brunet AC, Benyahya S, Serino M, Valle C, Ortiz MR, Puig J, Courtney M, Federici M, Fernández-Real JM, Burcelin R, Amar J. Changes in blood microbiota profiles associated with liver fibrosis in obese patients: A pilot analysis. Hepatology. 2016 Dec;64(6):2015-2027.
