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Mini CV
Nathalie Vergnolle, directrice de recherche à l’INSERM, est depuis le 1er janvier 2016 à la tête de l’Institut de Recherche en Santé Digestive. Elle est également responsable de l’équipe «Gut Protease Signals ».
Avant de mener ses recherches à Toulouse, le Dr Vergnolle a passé 10 ans à l'Université de Calgary (Canada) au sein du département de Pharmacologie. Ses travaux ont permis de mettre en évidence le rôle de plusieurs médiateurs impliqués dans l'inflammation et la douleur. En collaboration avec des chercheurs de l’INRAe et de l’Institut Pasteur, son équipe a produit des bactéries capables de protéger l’organisme des inflammations intestinales à partir d'une protéine humaine, l’Élafine. Ses recherches lui ont valu une reconnaissance internationale et sont soutenues au niveau européen, national et régional. Elles ont mené à des collaborations académiques et privées très actives.
Nathalie Vergnolle, research director at INSERM, is since 1 January 2016 as head of the Research Institute for Digestive Health. She is also responsible for the team "Gut Protease Signals"
Before conducting her research in Toulouse, Dr. Vergnolle spent 10 years at the University of Calgary (Canada) in the Department of Pharmacology. Her work has highlighted the role of several mediators involved in inflammation and pain. In collaboration with researchers from INRAe and the Pasteur Institute, her team produced bacteria expressing a human protein, elafin that can protect the body from intestinal inflammation. Her researches have earned him international recognition and are supported at European, national and regional level. They have led to very active academic and private collaborations .
FORMATION
• 1997 : Doctorat en Sciences biologiques, Université Toulouse III, France, Laboratoire de pharmacologie de l’INRA (direction L. Bueno)
POSITIONS
• 1997-2000 : Stage Post-doctoral, Université de Calgary, Canada, Laboratoire de John Wallace
• 2000 : Nommée Assistant Professor, Université de Calgary, Canada
• 2004 : Nommée Associate Professor, Université de Calgary, Canada
• 2007 : Nommée Directrice de Recherche 2ème classe INSERM, Toulouse, direction d’une équipe INSERM-AVENIR soutenue par la fondation Bettencourt-Schueller.
• 2011 : Nommée Directrice de Recherche 1ère classe INSERM, Toulouse, leader d’une equipe INSERM.
• 2016 : Nommée Directrice de l’Institut de Recherche en Santé Digestive.
DISTINCTIONS
Grand Prix Marthe Condat 2020
Prix recherche inserm 2018
• Prix Coup d’Elan de la Recherche Scientifique Fondation Bettencourt Schueller 2016.
• Chevalier de la légion d'honneur, 2013
• Femme en Science de l’inflammation, International Association of Inflammation Societies, 2013
• Subvention du Conseil Européen de la Recherche (ERC Consolidator Grant), 2013
• Master Award en Gastroenterologie (Association de Gastroenterologie Americaine) 2006
Avant de mener ses recherches à Toulouse, le Dr Vergnolle a passé 10 ans à l'Université de Calgary (Canada) au sein du département de Pharmacologie. Ses travaux ont permis de mettre en évidence le rôle de plusieurs médiateurs impliqués dans l'inflammation et la douleur. En collaboration avec des chercheurs de l’INRAe et de l’Institut Pasteur, son équipe a produit des bactéries capables de protéger l’organisme des inflammations intestinales à partir d'une protéine humaine, l’Élafine. Ses recherches lui ont valu une reconnaissance internationale et sont soutenues au niveau européen, national et régional. Elles ont mené à des collaborations académiques et privées très actives.
Nathalie Vergnolle, research director at INSERM, is since 1 January 2016 as head of the Research Institute for Digestive Health. She is also responsible for the team "Gut Protease Signals"
Before conducting her research in Toulouse, Dr. Vergnolle spent 10 years at the University of Calgary (Canada) in the Department of Pharmacology. Her work has highlighted the role of several mediators involved in inflammation and pain. In collaboration with researchers from INRAe and the Pasteur Institute, her team produced bacteria expressing a human protein, elafin that can protect the body from intestinal inflammation. Her researches have earned him international recognition and are supported at European, national and regional level. They have led to very active academic and private collaborations .
FORMATION
• 1997 : Doctorat en Sciences biologiques, Université Toulouse III, France, Laboratoire de pharmacologie de l’INRA (direction L. Bueno)
POSITIONS
• 1997-2000 : Stage Post-doctoral, Université de Calgary, Canada, Laboratoire de John Wallace
• 2000 : Nommée Assistant Professor, Université de Calgary, Canada
• 2004 : Nommée Associate Professor, Université de Calgary, Canada
• 2007 : Nommée Directrice de Recherche 2ème classe INSERM, Toulouse, direction d’une équipe INSERM-AVENIR soutenue par la fondation Bettencourt-Schueller.
• 2011 : Nommée Directrice de Recherche 1ère classe INSERM, Toulouse, leader d’une equipe INSERM.
• 2016 : Nommée Directrice de l’Institut de Recherche en Santé Digestive.
DISTINCTIONS
Grand Prix Marthe Condat 2020
Prix recherche inserm 2018
• Prix Coup d’Elan de la Recherche Scientifique Fondation Bettencourt Schueller 2016.
• Chevalier de la légion d'honneur, 2013
• Femme en Science de l’inflammation, International Association of Inflammation Societies, 2013
• Subvention du Conseil Européen de la Recherche (ERC Consolidator Grant), 2013
• Master Award en Gastroenterologie (Association de Gastroenterologie Americaine) 2006
Recherche/projet research/project
Production scientifique scientific production
2021
astrointestinal biofilms in health and disease.
Motta JP, Wallace JL, Buret AG, Deraison C, Vergnolle N.
Nat Rev Gastroenterol Hepatol. 2021 May;18(5):314-334. doi: 10.1038/s41575-020-00397-y. Epub 2021 Jan 28.
PMID: 33510461 Review.
GSK3β, a Master Kinase in the Regulation of Adult Stem Cell Behavior.
Racaud-Sultan C, Vergnolle N.
Cells. 2021 Jan 24;10(2):225. doi: 10.3390/cells10020225.
PMID: 33498808 Free PMC article. Review.
Increased Mucosal Thrombin is Associated with Crohn's Disease and Causes Inflammatory Damage through Protease-activated Receptors Activation.
Motta JP, Palese S, Giorgio C, Chapman K, Denadai-Souza A, Rousset P, Sagnat D, Guiraud L, Edir A, Seguy C, Alric L, Bonnet D, Bournet B, Buscail L, Gilletta C, Buret AG, Wallace JL, Hollenberg MD, Oswald E, Barocelli E, Le Grand S, Le Grand B, Deraison C, Vergnolle N.
J Crohns Colitis. 2021 May 4;15(5):787-799. doi: 10.1093/ecco-jcc/jjaa229.
PMID: 33201214 Free PMC article.
Colitis-linked to endoplasmic reticulum stress induces trypsin activity affecting epithelial functions.
Tapias NS, Denadai-Souza A, Rolland-Fourcade C, Quaranta-Nicaise M, Blanpied C, Marcellin M, Edir A, Rolland C, Cirillo C, Dietrich G, Alric L, Portier G, Kirzin S, Bonnet D, Mas E, Burlet-Schiltz O, Deraison C, Bonnart C, Vergnolle N, Barreau F.
J Crohns Colitis. 2021 Feb 20:jjab035. doi: 10.1093/ecco-jcc/jjab035. Online ahead of print.
PMID: 33609354
Epithelial production of elastase is increased in inflammatory bowel disease and causes mucosal inflammation.
Motta JP, Rolland C, Edir A, Florence AC, Sagnat D, Bonnart C, Rousset P, Guiraud L, Quaranta-Nicaise M, Mas E, Bonnet D, Verdu EF, McKay DM, Buscail E, Alric L, Vergnolle N, Deraison C.
Mucosal Immunol. 2021 May;14(3):667-678. doi: 10.1038/s41385-021-00375-w. Epub 2021 Mar 5.
PMID: 33674762 Free PMC article.
Towards a Large-Scale Assessment of the Relationship between Biological and Chronological Aging: The INSPIRE Mouse Cohort.
Santin Y, Lopez S, Ader I, Andrieu S, Blanchard N, Carrière A, Casteilla L, Cousin B, Davezac N, De Souto Barreto P, Dray C, Fazilleau N, Gonzalez-Dunia D, Gourdy P, Guyonnet S, Jabrane-Ferrat N, Kunduzova O, Lezoualc'h F, Liblau R, Martinez LO, Moro C, Payoux P, Pénicaud L, Planat-Bénard V, Rampon C, Rolland Y, Schanstra JP, Sierra F, Valet P, Varin A, Vergnolle N, Vellas B, Viña J, Guiard BP, Parini A.
J Frailty Aging. 2021;10(2):121-131. doi: 10.14283/jfa.2020.43.
PMID: 33575700
The INSPIRE Bio-Resource Research Platform for Healthy Aging and Geroscience: Focus on the Human Translational Research Cohort (The INSPIRE-T Cohort).
Guyonnet S, Rolland Y, Takeda C, Ousset PJ, Ader I, Davezac N, Dray C, Fazilleau N, Gourdy P, Liblau R, Parini A, Payoux P, Pénicaud L, Rampon C, Valet P, Vergnolle N, Andrieu S, de Souto Barreto P, Casteilla L, Vellas B.
J Frailty Aging. 2021;10(2):110-120. doi: 10.14283/jfa.2020.38.
PMID: 33575699 Free PMC article.
Gut mucosa alterations and loss of segmented filamentous bacteria in type 1 diabetes are associated with inflammation rather than hyperglycaemia.
Rouland M, Beaudoin L, Rouxel O, Bertrand L, Cagninacci L, Saffarian A, Pedron T, Gueddouri D, Guilmeau S, Burnol AF, Rachdi L, Tazi A, Mouriès J, Rescigno M, Vergnolle N, Sansonetti P, Christine Rogner U, Lehuen A.
Gut. 2021 Feb 16:gutjnl-2020-323664. doi: 10.1136/gutjnl-2020-323664. Online ahead of print.
PMID: 33593807
The INSPIRE Research Initiative: A Program for GeroScience and Healthy Aging Research Going from Animal Models to Humans and the Healthcare System.
de Souto Barreto P, Guyonnet S, Ader I, Andrieu S, Casteilla L, Davezac N, Dray C, Fazilleau N, Gourdy P, Liblau R, Parini A, Payoux P, Pénicaud L, Rampon C, Rolland Y, Valet P, Vergnolle N, Vellas B.
J Frailty Aging. 2021;10(2):86-93. doi: 10.14283/jfa.2020.18.
PMID: 33575696
Motta JP, Wallace JL, Buret AG, Deraison C, Vergnolle N.
Nat Rev Gastroenterol Hepatol. 2021 May;18(5):314-334. doi: 10.1038/s41575-020-00397-y. Epub 2021 Jan 28.
PMID: 33510461 Review.
GSK3β, a Master Kinase in the Regulation of Adult Stem Cell Behavior.
Racaud-Sultan C, Vergnolle N.
Cells. 2021 Jan 24;10(2):225. doi: 10.3390/cells10020225.
PMID: 33498808 Free PMC article. Review.
Increased Mucosal Thrombin is Associated with Crohn's Disease and Causes Inflammatory Damage through Protease-activated Receptors Activation.
Motta JP, Palese S, Giorgio C, Chapman K, Denadai-Souza A, Rousset P, Sagnat D, Guiraud L, Edir A, Seguy C, Alric L, Bonnet D, Bournet B, Buscail L, Gilletta C, Buret AG, Wallace JL, Hollenberg MD, Oswald E, Barocelli E, Le Grand S, Le Grand B, Deraison C, Vergnolle N.
J Crohns Colitis. 2021 May 4;15(5):787-799. doi: 10.1093/ecco-jcc/jjaa229.
PMID: 33201214 Free PMC article.
Colitis-linked to endoplasmic reticulum stress induces trypsin activity affecting epithelial functions.
Tapias NS, Denadai-Souza A, Rolland-Fourcade C, Quaranta-Nicaise M, Blanpied C, Marcellin M, Edir A, Rolland C, Cirillo C, Dietrich G, Alric L, Portier G, Kirzin S, Bonnet D, Mas E, Burlet-Schiltz O, Deraison C, Bonnart C, Vergnolle N, Barreau F.
J Crohns Colitis. 2021 Feb 20:jjab035. doi: 10.1093/ecco-jcc/jjab035. Online ahead of print.
PMID: 33609354
Epithelial production of elastase is increased in inflammatory bowel disease and causes mucosal inflammation.
Motta JP, Rolland C, Edir A, Florence AC, Sagnat D, Bonnart C, Rousset P, Guiraud L, Quaranta-Nicaise M, Mas E, Bonnet D, Verdu EF, McKay DM, Buscail E, Alric L, Vergnolle N, Deraison C.
Mucosal Immunol. 2021 May;14(3):667-678. doi: 10.1038/s41385-021-00375-w. Epub 2021 Mar 5.
PMID: 33674762 Free PMC article.
Towards a Large-Scale Assessment of the Relationship between Biological and Chronological Aging: The INSPIRE Mouse Cohort.
Santin Y, Lopez S, Ader I, Andrieu S, Blanchard N, Carrière A, Casteilla L, Cousin B, Davezac N, De Souto Barreto P, Dray C, Fazilleau N, Gonzalez-Dunia D, Gourdy P, Guyonnet S, Jabrane-Ferrat N, Kunduzova O, Lezoualc'h F, Liblau R, Martinez LO, Moro C, Payoux P, Pénicaud L, Planat-Bénard V, Rampon C, Rolland Y, Schanstra JP, Sierra F, Valet P, Varin A, Vergnolle N, Vellas B, Viña J, Guiard BP, Parini A.
J Frailty Aging. 2021;10(2):121-131. doi: 10.14283/jfa.2020.43.
PMID: 33575700
The INSPIRE Bio-Resource Research Platform for Healthy Aging and Geroscience: Focus on the Human Translational Research Cohort (The INSPIRE-T Cohort).
Guyonnet S, Rolland Y, Takeda C, Ousset PJ, Ader I, Davezac N, Dray C, Fazilleau N, Gourdy P, Liblau R, Parini A, Payoux P, Pénicaud L, Rampon C, Valet P, Vergnolle N, Andrieu S, de Souto Barreto P, Casteilla L, Vellas B.
J Frailty Aging. 2021;10(2):110-120. doi: 10.14283/jfa.2020.38.
PMID: 33575699 Free PMC article.
Gut mucosa alterations and loss of segmented filamentous bacteria in type 1 diabetes are associated with inflammation rather than hyperglycaemia.
Rouland M, Beaudoin L, Rouxel O, Bertrand L, Cagninacci L, Saffarian A, Pedron T, Gueddouri D, Guilmeau S, Burnol AF, Rachdi L, Tazi A, Mouriès J, Rescigno M, Vergnolle N, Sansonetti P, Christine Rogner U, Lehuen A.
Gut. 2021 Feb 16:gutjnl-2020-323664. doi: 10.1136/gutjnl-2020-323664. Online ahead of print.
PMID: 33593807
The INSPIRE Research Initiative: A Program for GeroScience and Healthy Aging Research Going from Animal Models to Humans and the Healthcare System.
de Souto Barreto P, Guyonnet S, Ader I, Andrieu S, Casteilla L, Davezac N, Dray C, Fazilleau N, Gourdy P, Liblau R, Parini A, Payoux P, Pénicaud L, Rampon C, Rolland Y, Valet P, Vergnolle N, Vellas B.
J Frailty Aging. 2021;10(2):86-93. doi: 10.14283/jfa.2020.18.
PMID: 33575696
2020
racterization of Human Colon Organoids From Inflammatory Bowel Disease Patients.
d'Aldebert E, Quaranta M, Sébert M, Bonnet D, Kirzin S, Portier G, Duffas JP, Chabot S, Lluel P, Allart S, Ferrand A, Alric L, Racaud-Sultan C, Mas E, Deraison C, Vergnolle N.
Front Cell Dev Biol. 2020 Jun 4;8:363. doi: 10.3389/fcell.2020.00363. eCollection 2020.
PMID: 32582690 Free PMC article.
Revisiting the Hallmarks of Aging to Identify Markers of Biological Age.
Guerville F, De Souto Barreto P, Ader I, Andrieu S, Casteilla L, Dray C, Fazilleau N, Guyonnet S, Langin D, Liblau R, Parini A, Valet P, Vergnolle N, Rolland Y, Vellas B.
J Prev Alzheimers Dis. 2020;7(1):56-64. doi: 10.14283/jpad.2019.50.
PMID: 32010927 Review.
Colon-specific immune microenvironment regulates cancer progression versus rejection.
Trimaglio G, Tilkin-Mariamé AF, Feliu V, Lauzéral-Vizcaino F, Tosolini M, Valle C, Ayyoub M, Neyrolles O, Vergnolle N, Rombouts Y, Devaud C.
Oncoimmunology. 2020 Jul 12;9(1):1790125. doi: 10.1080/2162402X.2020.1790125.
PMID: 32923152 Free PMC article.
The Interplay Between Genetic Risk Factors and Proteolytic Dysregulation in the Pathophysiology of Inflammatory Bowel Disease.
Solà-Tapias N, Vergnolle N, Denadai-Souza A, Barreau F.
J Crohns Colitis. 2020 Sep 7;14(8):1149-1161. doi: 10.1093/ecco-jcc/jjaa033.
PMID: 32090263 Review.
Daphnanes diterpenes from the latex of Hura crepitans L. And activity against human colorectal cancer cells Caco-2.
Trinel M, Le Lamer AC, Jullian V, Jacquemin D, Graton J, Cristofoli V, Crossay E, Yassine M, Rolland C, Vergnolle N, Mejia K, Joel Cabanillas B, Racaud-Sultan C, Fabre N.
Bioorg Chem. 2020 Oct;103:104132. doi: 10.1016/j.bioorg.2020.104132. Epub 2020 Jul 23.
PMID: 32768743
Characterization and Validation of a Chronic Model of Cyclophosphamide-Induced Interstitial Cystitis/Bladder Pain Syndrome in Rats.
Augé C, Gamé X, Vergnolle N, Lluel P, Chabot S.
Front Pharmacol. 2020 Aug 28;11:1305. doi: 10.3389/fphar.2020.01305. eCollection 2020.
PMID: 32982733 Free PMC article.
Culture of rabbit caecum organoids by reconstituting the intestinal stem cell niche in vitro with pharmacological inhibitors or L-WRN conditioned medium.
Mussard E, Pouzet C, Helies V, Pascal G, Fourre S, Cherbuy C, Rubio A, Vergnolle N, Combes S, Beaumont M.
Stem Cell Res. 2020 Oct;48:101980. doi: 10.1016/j.scr.2020.101980. Epub 2020 Sep 4.
PMID: 32920507
Gut mucosa alterations and loss of segmented filamentous bacteria in type 1 diabetes are associated with inflammation rather than hyperglycaemia.
Rouland M, Beaudoin L, Rouxel O, Bertrand L, Cagninacci L, Saffarian A, Pedron T, Gueddouri D, Guilmeau S, Burnol AF, Rachdi L, Tazi A, Mouriès J, Rescigno M, Vergnolle N, Sansonetti P, Christine Rogner U, Lehuen A.
Gut. 2021 Feb 16:gutjnl-2020-323664. doi: 10.1136/gutjnl-2020-323664. Online ahead of print.
PMID: 33593807
d'Aldebert E, Quaranta M, Sébert M, Bonnet D, Kirzin S, Portier G, Duffas JP, Chabot S, Lluel P, Allart S, Ferrand A, Alric L, Racaud-Sultan C, Mas E, Deraison C, Vergnolle N.
Front Cell Dev Biol. 2020 Jun 4;8:363. doi: 10.3389/fcell.2020.00363. eCollection 2020.
PMID: 32582690 Free PMC article.
Revisiting the Hallmarks of Aging to Identify Markers of Biological Age.
Guerville F, De Souto Barreto P, Ader I, Andrieu S, Casteilla L, Dray C, Fazilleau N, Guyonnet S, Langin D, Liblau R, Parini A, Valet P, Vergnolle N, Rolland Y, Vellas B.
J Prev Alzheimers Dis. 2020;7(1):56-64. doi: 10.14283/jpad.2019.50.
PMID: 32010927 Review.
Colon-specific immune microenvironment regulates cancer progression versus rejection.
Trimaglio G, Tilkin-Mariamé AF, Feliu V, Lauzéral-Vizcaino F, Tosolini M, Valle C, Ayyoub M, Neyrolles O, Vergnolle N, Rombouts Y, Devaud C.
Oncoimmunology. 2020 Jul 12;9(1):1790125. doi: 10.1080/2162402X.2020.1790125.
PMID: 32923152 Free PMC article.
The Interplay Between Genetic Risk Factors and Proteolytic Dysregulation in the Pathophysiology of Inflammatory Bowel Disease.
Solà-Tapias N, Vergnolle N, Denadai-Souza A, Barreau F.
J Crohns Colitis. 2020 Sep 7;14(8):1149-1161. doi: 10.1093/ecco-jcc/jjaa033.
PMID: 32090263 Review.
Daphnanes diterpenes from the latex of Hura crepitans L. And activity against human colorectal cancer cells Caco-2.
Trinel M, Le Lamer AC, Jullian V, Jacquemin D, Graton J, Cristofoli V, Crossay E, Yassine M, Rolland C, Vergnolle N, Mejia K, Joel Cabanillas B, Racaud-Sultan C, Fabre N.
Bioorg Chem. 2020 Oct;103:104132. doi: 10.1016/j.bioorg.2020.104132. Epub 2020 Jul 23.
PMID: 32768743
Characterization and Validation of a Chronic Model of Cyclophosphamide-Induced Interstitial Cystitis/Bladder Pain Syndrome in Rats.
Augé C, Gamé X, Vergnolle N, Lluel P, Chabot S.
Front Pharmacol. 2020 Aug 28;11:1305. doi: 10.3389/fphar.2020.01305. eCollection 2020.
PMID: 32982733 Free PMC article.
Culture of rabbit caecum organoids by reconstituting the intestinal stem cell niche in vitro with pharmacological inhibitors or L-WRN conditioned medium.
Mussard E, Pouzet C, Helies V, Pascal G, Fourre S, Cherbuy C, Rubio A, Vergnolle N, Combes S, Beaumont M.
Stem Cell Res. 2020 Oct;48:101980. doi: 10.1016/j.scr.2020.101980. Epub 2020 Sep 4.
PMID: 32920507
Gut mucosa alterations and loss of segmented filamentous bacteria in type 1 diabetes are associated with inflammation rather than hyperglycaemia.
Rouland M, Beaudoin L, Rouxel O, Bertrand L, Cagninacci L, Saffarian A, Pedron T, Gueddouri D, Guilmeau S, Burnol AF, Rachdi L, Tazi A, Mouriès J, Rescigno M, Vergnolle N, Sansonetti P, Christine Rogner U, Lehuen A.
Gut. 2021 Feb 16:gutjnl-2020-323664. doi: 10.1136/gutjnl-2020-323664. Online ahead of print.
PMID: 33593807
2019
Multi-hit early life adversity affects gut microbiota, brain and behavior in a sex-dependent manner.
Rincel M, Aubert P, Chevalier J, Grohard PA, Basso L, Monchaux de Oliveira C, Helbling JC, Lévy É, Chevalier G, Leboyer M, Eberl G, Layé S, Capuron L, Vergnolle N, Neunlist M, Boudin H, Lepage P, Darnaudéry M.
Brain Behav Immun. 2019 Aug;80:179-192. doi: 10.1016/j.bbi.2019.03.006. Epub 2019 Mar 11.
PMID: 30872090
Aluminum Ingestion Promotes Colorectal Hypersensitivity in Rodents.
Esquerre N, Basso L, Dubuquoy C, Djouina M, Chappard D, Blanpied C, Desreumaux P, Vergnolle N, Vignal C, Body-Malapel M.
Cell Mol Gastroenterol Hepatol. 2018 Sep 20;7(1):185-196. doi: 10.1016/j.jcmgh.2018.09.012. eCollection 2019.
PMID: 30534582 Free PMC article.
Sexual dimorphism in PAR2-dependent regulation of primitive colonic cells.
Noguerol J, Roustan PJ, N'Taye M, Delcombel L, Rolland C, Guiraud L, Sagnat D, Edir A, Bonnart C, Denadai-Souza A, Deraison C, Vergnolle N, Racaud-Sultan C.
Biol Sex Differ. 2019 Sep 6;10(1):47. doi: 10.1186/s13293-019-0262-6.
PMID: 31492202 Free PMC article.
Active thrombin produced by the intestinal epithelium controls mucosal biofilms.
Motta JP, Denadai-Souza A, Sagnat D, Guiraud L, Edir A, Bonnart C, Sebbag M, Rousset P, Lapeyre A, Seguy C, Mathurine-Thomas N, Galipeau HJ, Bonnet D, Alric L, Buret AG, Wallace JL, Dufour A, Verdu EF, Hollenberg MD, Oswald E, Serino M, Deraison C, Vergnolle N.
Nat Commun. 2019 Jul 19;10(1):3224. doi: 10.1038/s41467-019-11140-w.
PMID: 31324782 Free PMC article.
FAK alternative splice mRNA variants expression pattern in colorectal cancer.
Devaud C, Tilkin-Mariamé AF, Vignolle-Vidoni A, Souleres P, Denadai-Souza A, Rolland C, Duthoit C, Blanpied C, Chabot S, Bouillé P, Lluel P, Vergnolle N, Racaud-Sultan C, Ferrand A.
Int J Cancer. 2019 Jul 15;145(2):494-502. doi: 10.1002/ijc.32120. Epub 2019 Feb 14.
PMID: 30628725 Free PMC article.
Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2.
Caminero A, McCarville JL, Galipeau HJ, Deraison C, Bernier SP, Constante M, Rolland C, Meisel M, Murray JA, Yu XB, Alaedini A, Coombes BK, Bercik P, Southward CM, Ruf W, Jabri B, Chirdo FG, Casqueiro J, Surette MG, Vergnolle N, Verdu EF.
Nat Commun. 2019 Mar 13;10(1):1198. doi: 10.1038/s41467-019-09037-9.
PMID: 30867416 Free PMC article.
Sustainable Positive Response to Sirolimus in Juvenile Polyposis of Infancy.
Quaranta M, Laborde N, Ferrand A, Danjoux M, Vergnolle N, Barreau F, Racaud-Sultan C, Mas E.
J Pediatr Gastroenterol Nutr. 2019 Feb;68(2):e38-e40. doi: 10.1097/MPG.0000000000002179.
PMID: 30334931 No abstract available.
The INSPIRE Bio-Resource Research Platform for Healthy Aging and Geroscience: Focus on the Human Translational Research Cohort (The INSPIRE-T Cohort).
Guyonnet S, Rolland Y, Takeda C, Ousset PJ, Ader I, Davezac N, Dray C, Fazilleau N, Gourdy P, Liblau R, Parini A, Payoux P, Pénicaud L, Rampon C, Valet P, Vergnolle N, Andrieu S, de Souto Barreto P, Casteilla L, Vellas B.
J Frailty Aging. 2021;10(2):110-120. doi: 10.14283/jfa.2020.38.
PMID: 33575699 Free PMC article.
Rincel M, Aubert P, Chevalier J, Grohard PA, Basso L, Monchaux de Oliveira C, Helbling JC, Lévy É, Chevalier G, Leboyer M, Eberl G, Layé S, Capuron L, Vergnolle N, Neunlist M, Boudin H, Lepage P, Darnaudéry M.
Brain Behav Immun. 2019 Aug;80:179-192. doi: 10.1016/j.bbi.2019.03.006. Epub 2019 Mar 11.
PMID: 30872090
Aluminum Ingestion Promotes Colorectal Hypersensitivity in Rodents.
Esquerre N, Basso L, Dubuquoy C, Djouina M, Chappard D, Blanpied C, Desreumaux P, Vergnolle N, Vignal C, Body-Malapel M.
Cell Mol Gastroenterol Hepatol. 2018 Sep 20;7(1):185-196. doi: 10.1016/j.jcmgh.2018.09.012. eCollection 2019.
PMID: 30534582 Free PMC article.
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